The role of brain-derived neurotrophic factor in immune-related diseases: a narrative review

M Sochal, M Ditmer, A Gabryelska… - Journal of Clinical …, 2022 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is a neurotrophin regulating synaptic plasticity,
neuronal excitability, and nociception. It seems to be one of the key molecules in interactions …

Molecular mechanisms underlying cyclophosphamide-induced cognitive impairment and strategies for neuroprotection in preclinical models

KM Ibrahim, SF Darwish, EM Mantawy… - Molecular and Cellular …, 2023 - Springer
Cyclophosphamide has drastically enhanced the expectancy and quality of life of cancer
patients. However, it is accompanied by diverse neurological complications which are …

Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …

[HTML][HTML] Bioactive compounds from Actinidia arguta fruit as a new strategy to fight glioblastoma

C Macedo, PC Costa, F Rodrigues - Food Research International, 2023 - Elsevier
In recent years, there has been a significant demand for natural products as a mean of
disease prevention or as an alternative to conventional medications. The driving force for …

[HTML][HTML] Antitumor activity of ferulic acid against Ehrlich solid carcinoma in rats via affecting hypoxia, oxidative stress and cell proliferation

MA Alghamdi, TA Khalifah, HS Alhawati, M Ruzayq… - Cureus, 2023 - ncbi.nlm.nih.gov
Background Ferulic acid is a natural compound commonly found in fruits and vegetables like
tomatoes, sweet corn, rice bran, and dong quai. It has various beneficial effects on the body …

Waste to wealth: microbial-based valorization of grape pomace for nutraceutical, cosmetic, and therapeutic applications to promote circular economy

GK Sodhi, G Kaur, N George, HK Walia, D Sillu… - Process Safety and …, 2024 - Elsevier
Grape pomace, the solid residue produced during fruit extraction, is a significant by-product
of the wine industry. The industry generates vast amounts of grape pomace each year …

Recent advances in neuroinflammation prevention and therapy: the role of natural products and underlying mechanisms based on molecular targets

MM Zhao, JY Duan, Y Shen, Y Liu… - British Journal of …, 2024 - Wiley Online Library
Neuroinflammation is initiated in response to a variety of endogenous and exogenous
sources. As the resident macrophages of the central nervous system, the polarization of …

Irbesartan mitigates the impact of cyclophosphamide-induced acute neurotoxicity in rats: Shedding highlights on NLRP3 inflammasome/CASP-1 pathway-driven …

RH Abu-Baih, MFG Ibrahim, EY Elhamadany… - International …, 2024 - Elsevier
IIrbesartan (IRB), an angiotensin II type 1 receptor (AT1R) antagonist, has been widely
employed in the medical field for its effectiveness in managing hypertension. However, there …

An Updated Review on Nelumbo Nucifera Gaertn: Chemical Composition, Nutritional Value and Pharmacological Activities

B Sahu, M Sahu, M Sahu, M Yadav… - Chemistry & …, 2024 - Wiley Online Library
Nelumbo nucifera Gaertn is a recognised herbal plant in ancient medical sciences. Each
portion of the plant leaf, flower, seed and rhizome is utilised for nutritional and medicinal …

Neuroprotective potential of Ginkgo biloba on alteration of rat cerebellum following prenatal exposure to cyclophosphamide

SHW Weli, A Yahyazadeh - Journal of Chemical Neuroanatomy, 2023 - Elsevier
The cytotoxicity of chemotherapeutic drugs is known due to its non-selective effect not only
on cancer cells but also on healthy cells. This study investigated the cerebellar alteration in …