Diagnosis and management of bipolar disorders

FS Goes - bmj, 2023 - bmj.com
Bipolar disorders (BDs) are recurrent and sometimes chronic disorders of mood that affect
around 2% of the world's population and encompass a spectrum between severe elevated …

Transdiagnostic risk of mental disorders in offspring of affected parents: a meta‐analysis of family high‐risk and registry studies

R Uher, B Pavlova, J Radua, U Provenzani… - World …, 2023 - Wiley Online Library
The offspring of parents with mental disorders are at increased risk for developing mental
disorders themselves. The risk to offspring may extend transdiagnostically to disorders other …

A systematic review and meta-analysis of global and social functioning among people at risk of bipolar disorder

M Watson, K Filia, A Stevens, S Cotton, B Nelson… - Journal of Affective …, 2023 - Elsevier
Background Functional status could predict development of bipolar disorder (BD) or have
clinical significance. The relationship between BD risk and functioning is poorly understood …

Maternal inflammation during pregnancy is associated with risk of ADHD in children at age 10

JB Rosenberg, JRM Jepsen… - Brain, Behavior, and …, 2024 - Elsevier
Introduction Maternal inflammation during pregnancy may affect early neurodevelopment in
offspring as suggested by preclinical and register data. However, clinical evidence for risk of …

[HTML][HTML] High-dose vitamin D3 supplementation in pregnancy and risk of neurodevelopmental disorders in the children at age 10: A randomized clinical trial

K Aagaard, JRM Jepsen, A Sevelsted, D Horner… - The American journal of …, 2024 - Elsevier
Background Vitamin D deficiency in pregnancy may increase the risk of autism and attention
deficit hyperactivity disorder (ADHD). Objective The objective of this study was to estimate …

Developmental pathways and clinical outcomes of early childhood psychotic experiences in preadolescent children at familial high risk of schizophrenia or bipolar …

M Gregersen, JR Møllegaard Jepsen… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Psychotic experiences are common in children and adolescents and are
associated with concurrent and subsequent psychopathology. Most findings originate from …

Childhood trauma in children at familial high risk of schizophrenia or bipolar disorder: A longitudinal study. The Danish High Risk and Resilience Study–VIA 7 and VIA …

JM Brandt, N Hemager, M Gregersen… - British Journal of …, 2022 - Wiley Online Library
Objectives Childhood trauma increases the risk of developing mental illness as does being
born to parents with schizophrenia or bipolar disorder. We aimed to compare prevalence of …

[HTML][HTML] COVID-19 lockdown, genetic ADHD susceptibility, and mental health in 10-year-old children

M Hernández-Lorca, A Sevelsted, JRM Jepsen… - Psychiatry …, 2023 - Elsevier
Previous studies report that the COVID-19 lockdown had an impact on the mental health of
the pediatric population. In this study, we harness the deep neuropsychiatric phenotyping of …

Children at familial high risk of schizophrenia and bipolar disorder exhibit altered connectivity patterns during pre-attentive processing of an auditory prediction error

KM Larsen, KS Madsen… - Schizophrenia …, 2024 - academic.oup.com
Abstract Background and Hypothesis Individuals with schizophrenia or bipolar disorder
have attenuated auditory mismatch negativity (MMN) responses, indicating impaired …

[HTML][HTML] Functional outcomes across development in offspring of parents with bipolar disorder

FGL Helmink, CL Vandeleur, M Preisig… - Journal of Affective …, 2023 - Elsevier
Objective Whereas the risk and course of psychopathology in offspring of parents with
bipolar disorder (BD) have been the primary focus of high-risk offspring studies to date …