Food components have long been recognized to play a fundamental role in the growth and
development of the human body, conferring protective functionalities against foreign matter …

Sickle cell anaemia (SCD) is a life-threatening haematological disorder which is
predominant in sub-Saharan Africa and is triggered by a genetic mutation of the β-chain …

Endometriosis is an estrogen-dependent, progesterone-resistant gynecological disease with
an unknown pathogenesis. Compared to women without endometriosis, women with …

Heme oxygenase (HO-1) mediates the enzymatic cleavage of heme, a molecule with
proinflammatory and prooxidant properties. HO-1 activity deeply impacts host capacity to …

Leishmaniases are neglected diseases, caused by intracellular protozoan parasites of the
Leishmania (L.) genus. Although the principal host cells of the parasites are macrophages …

Neutrophils with their array of microbicidal activities are the first innate immune cells to
guard against infection. They are also most crucial for the host's initial defense against …

Necroptosis is a pro-inflammatory cell death, which happens in the context of caspase-8
inhibition, allowing activation of the receptor interacting protein kinase 1–receptor interacting …

High-level production of recombinant proteins in industrial microorganisms is often limited
by the formation of misfolded proteins or protein aggregates, which consequently induce …

Simple Summary Heme is an iron-containing porphyrin that functions as a prosthetic group
in hemoproteins and is involved in many biological processes. This review article …

Sickle cell disease (SCD) is the most severe monogenic hemoglobinopathy caused by a
single genetic mutation that leads to repeated polymerization and depolymerization of …