The use of plant secondary metabolites has gained considerable attention among clinicians
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …

The natural lignan podophyllotoxin, a dimerized product of two phenylpropanoid moieties
which occurs in a few plant species, is a pharmacologically important compound for its …

Juniperus excelsa M. Bieb and J. sabina L. contain essential oil (EO), while J. sabina also
contains podophyllotoxin, which is used as a precursor for anti-cancer drugs. Two studies …

Many North American plants have characteristics that are especially promising for creating
varieties needed to expand food production, and there are excellent prospects of generating …

Podophyllotoxin is an aryltetralin lignan synthesized in several plant species, which is used
in chemotherapies for cancers and tumor treatment. More potent semisynthetic derivatives of …

Malignant diseases are the second mortality cause within the human population. Despite the
serious progress in establishing and introduction of novel specifically targeted drugs the …

Introduction Traditional medicine has traditionally appreciated the use of Podophyllum
peltatum, a large herbaceous species with origins in eastern United States and southern …

Podophyllotoxin is currently in high demand as the lead chemical precursor for the anti-
cancer drugs etoposide and teniposide. We conducted a two-phase study:(i) screening of …

Camptothecin (CPT) is a potent anti-tumour isoquinoline alkaloid used extensively in the
treatment of several cancers. Among several plant species known to contain the compound …

Camptothecin (CPT), a pyrrolo quinoline alkaloid, is one of the most promising anticancer
drugs of the 21st century. The compound was first isolated from the Chinese deciduous tree …