The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …

The modern antiretroviral treatment of human immunodeficiency virus (HIV-1) infection has
considerably lowered the incidence of opportunistic infections. With the exception of the …

Current approaches to classifying cognitive impairment in people living with HIV can
overestimate disease burden and lead to ambiguity around disease mechanisms. The 2007 …

Alcohol use is common among people living with human immunodeficiency virus (HIV). In
this narrative review, we describe literature regarding alcohol's impact on transmission, care …

Background: The HIV associated mortality is decreasing in most countries due to the
widespread use of antiretroviral therapy. However, HIV-associated neurocognitive disorder …

Abstract In 2019, the National Institutes of Health combined the Multicenter AIDS Cohort
Study (MACS) and the Women's Interagency HIV Study (WIHS) into the MACS/WIHS …

The choroid plexus is situated at an anatomically and functionally important interface within
the ventricles of the brain, forming the blood-cerebrospinal fluid barrier that separates the …

HIV-associated neurological disorders (HAND) affect up to 50% of people living with HIV
(PLWH), even in the era of combination antiretroviral therapy (cART). HIV-DNA can be …

Background HIV-associated neurocognitive disorders are common in people living with
HIV/AIDS and affect the adherence of patients to prescriptions, activities of daily living, and …