Recovery of neuronal and network excitability after spinal cord injury and implications for spasticity

JM D'amico, EG Condliffe, KJB Martins… - Frontiers in integrative …, 2014 - frontiersin.org
The state of areflexia and muscle weakness that immediately follows a spinal cord injury
(SCI) is gradually replaced by the recovery of neuronal and network excitability, leading to …

The effects of exercise and activity-based physical therapy on bone after spinal cord injury

TW Sutor, J Kura, AJ Mattingly, DM Otzel… - International Journal of …, 2022 - mdpi.com
Spinal cord injury (SCI) produces paralysis and a unique form of neurogenic disuse
osteoporosis that dramatically increases fracture risk at the distal femur and proximal tibia …

Muscle spindle feedback directs locomotor recovery and circuit reorganization after spinal cord injury

A Takeoka, I Vollenweider, G Courtine, S Arber - Cell, 2014 - cell.com
Spinal cord injuries alter motor function by disconnecting neural circuits above and below
the lesion, rendering sensory inputs a primary source of direct external drive to neuronal …

Propriospinal neurons: essential elements of locomotor control in the intact and possibly the injured spinal cord

AM Laliberte, S Goltash, NR Lalonde… - Frontiers in Cellular …, 2019 - frontiersin.org
Propriospinal interneurons (INs) communicate information over short and long distances
within the spinal cord. They act to coordinate different parts of the body by linking motor …

HAL® exoskeleton training improves walking parameters and normalizes cortical excitability in primary somatosensory cortex in spinal cord injury patients

M Sczesny-Kaiser, O Höffken, M Aach… - … of neuroengineering and …, 2015 - Springer
Background Reorganization in the sensorimotor cortex accompanied by increased
excitability and enlarged body representations is a consequence of spinal cord injury (SCI) …

A review on locomotor training after spinal cord injury: reorganization of spinal neuronal circuits and recovery of motor function

AC Smith, M Knikou - Neural plasticity, 2016 - Wiley Online Library
Locomotor training is a classic rehabilitation approach utilized with the aim of improving
sensorimotor function and walking ability in people with spinal cord injury (SCI). Recent …

Against the odds: what to expect in rehabilitation of chronic spinal cord injury with a neurologically controlled Hybrid Assistive Limb exoskeleton. A subgroup analysis …

D Grasmücke, A Zieriacks, O Jansen, C Fisahn… - Neurosurgical …, 2017 - thejns.org
Objective Age and lesion level are believed to represent outcome predictors in rehabilitation
of patients with chronic spinal cord injury (SCI). The Hybrid Assistive Limb (HAL) …

Electrical stimulation and motor recovery

W Young - Cell transplantation, 2015 - journals.sagepub.com
In recent years, several investigators have successfully regenerated axons in animal spinal
cords without locomotor recovery. One explanation is that the animals were not trained to …

Repeated transspinal stimulation decreases soleus H-reflex excitability and restores spinal inhibition in human spinal cord injury

M Knikou, LM Murray - PLoS One, 2019 - journals.plos.org
Transcutaneous spinal cord or transspinal stimulation over the thoracolumbar enlargement,
the spinal location of motoneurons innervating leg muscles, modulates neural circuits …

The use of surface EMG in neurorehabilitation following traumatic spinal cord injury: A scoping review

G Balbinot, MJ Wiest, G Li, M Pakosh, JC Furlan… - Clinical …, 2022 - Elsevier
Objective Surface electromyography (sEMG) is a common electrophysiological assessment
used in clinical trials in individuals with spinal cord injury (SCI). This scoping review …