Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …

Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …

Stress granules (SGs) are cytoplasmic assemblies of proteins and non-translating mRNAs.
Whereas much has been learned about SG formation, a major gap remains in …

Posttranscriptional gene expression including splicing, RNA transport, translation, and RNA
decay provides an important regulatory layer in many if not all molecular pathways …

ABSTRACT RNA-binding proteins are a critical group of multifunctional proteins that
precisely regulate all aspects of gene expression, from alternative splicing to mRNA …

Membrane‐less organelles, because of their capacity to dynamically, selectively and
reversibly concentrate molecules, are very well adapted for local information processing and …

Biomolecular condensates, membraneless organelles found throughout the cell, play critical
roles in many aspects of cellular function. Ribonucleoprotein granules (RNPs) are a type of …

Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and the
best-described monogenic cause of autism. CGG-repeat expansion in the FMR1 gene leads …

The timing, dosage and location of gene expression are fundamental determinants of brain
architectural complexity. In neurons, this is, primarily, achieved by specific sets of trans …

RNA granules are dynamic entities controlling the spatiotemporal distribution and translation
of RNA molecules. In neurons, a variety of RNA granules exist both in the soma and in …