Advancements in addressing drug dependence: A review of promising therapeutic strategies and interventions
CR Guida, JM Maia, LFR Ferreira, A Rahdar… - Progress in Neuro …, 2024 - Elsevier
Substance dependence represents a pervasive global concern within the realm of public
health. Presently, it is delineated as a persistent and recurrent neurological disorder …
health. Presently, it is delineated as a persistent and recurrent neurological disorder …
Mechanisms underlying microRNA-222-3p modulation of methamphetamine-induced conditioned place preference in the nucleus accumbens in mice
Q Shang, J Wang, Z Xi, B Gao, H Qian, R An… - …, 2022 - Springer
Rationale MicroRNA (miRNA) control of post-transcription gene expression in the nucleus
accumbens (NAc) has been implicated in methamphetamine (METH) dependence …
accumbens (NAc) has been implicated in methamphetamine (METH) dependence …
Akt and its phosphorylation in nucleus accumbens mediate heroin‐seeking behavior induced by cues in rats
H Zhu, D Zhuang, Z Lou, M Lai, D Fu, Q Hong… - Addiction …, 2021 - Wiley Online Library
Akt is initially identified as one of the downstream targets of phosphatidylinositol‐3 kinase
(PI3K) and is involved in morphine reward and tolerance. However, whether …
(PI3K) and is involved in morphine reward and tolerance. However, whether …
Maternal methamphetamine exposure influences behavioral sensitization and nucleus accumbens DNA methylation in subsequent generation
N Dong, J Zhu, R Wang, S Wang, Y Chen… - Frontiers in …, 2022 - frontiersin.org
The deleterious effects of methamphetamine (METH) exposure extend beyond abusers, and
may potentially impact the vulnerability of their offspring in developing addictive behaviors …
may potentially impact the vulnerability of their offspring in developing addictive behaviors …
The roles of K+-dependent Na+/Ca2+ exchanger 2 (NCKX2) in methamphetamine-induced behavioral sensitization and conditioned place preference in mice
M Liang, G Chen, Z Xi, H Qian, Q Shang, B Gao… - Neuroscience …, 2023 - Elsevier
Drug addiction, including methamphetamine (METH) addiction, is a significant public health
and social issue. Perturbations in intracellular Ca 2+ homeostasis are associated with drug …
and social issue. Perturbations in intracellular Ca 2+ homeostasis are associated with drug …
Effects of the GluN2B-selective antagonist Ro 63-1908 on acquisition and expression of methamphetamine conditioned place preference in male and female rats
JR Yates, HL Campbell, LL Hawley, MJ Horchar… - Drug and alcohol …, 2021 - Elsevier
Background Methamphetamine abuse has increased significantly in recent years. Currently,
there are no FDA-approved pharmacotherapies for the treatment of methamphetamine use …
there are no FDA-approved pharmacotherapies for the treatment of methamphetamine use …
The NR2B-targeted intervention alleviates the neuronal injuries at the sub-acute stage of cerebral ischemia: an exploration of stage-dependent strategy against …
B Guo, H Song, J Fan, B Wang, L Chen, Q Hu… - Experimental Brain …, 2023 - Springer
Stroke is reported to be the second leading cause of death worldwide, among which
ischemic stroke has fourfold greater incidence than intracerebral hemorrhage. Excitotoxicity …
ischemic stroke has fourfold greater incidence than intracerebral hemorrhage. Excitotoxicity …
Phosphorylation of GluN2B subunits of N-methyl-d-aspartate receptors in the frontal association cortex involved in morphine-induced conditioned place preference in …
Morphine is one of the most abused drugs in the world, which has resulted in serious social
problems. The frontal association cortex (FrA) has been shown to play a key role in memory …
problems. The frontal association cortex (FrA) has been shown to play a key role in memory …
PP2A-C may be a promising candidate for postmortem interval estimation
J Wang, G Chen, H Qian, Q Shang, J Xiao… - International Journal of …, 2021 - Springer
Determining the postmortem interval (PMI) is an important task in forensic pathology.
However, a reliable means of determining the PMI between 24 h and approximately 7 days …
However, a reliable means of determining the PMI between 24 h and approximately 7 days …
Spatiotemporal expression of Rap1 and Ras mediates the acquisition and reinstatement of methamphetamine-induced conditioned place preference in mice via …
H Qian, J Xiao, Q Shang, J Wang, M Liang, B Gao… - …, 2021 - journals.lww.com
Drug addiction is a chronic recurrent brain disease characterized by compulsive drug use
and a high tendency to relapse. We previously reported that the Ras-extracellular signal …
and a high tendency to relapse. We previously reported that the Ras-extracellular signal …