Progress in the mechanism and targeted drug therapy for COPD
C Wang, J Zhou, J Wang, S Li, A Fukunaga… - … and Targeted Therapy, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …
The role of MIF on eosinophil biology and eosinophilic inflammation
Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine that participates in
innate and adaptive immune responses. MIF contributes to the resistance against infection …
innate and adaptive immune responses. MIF contributes to the resistance against infection …
Human macrophage migration inhibitory factor potentiates mesenchymal stromal cell efficacy in a clinically relevant model of allergic asthma
IJ Hawthorne, H Dunbar, C Tunstead, T Schorpp… - Molecular Therapy, 2023 - cell.com
Current asthma therapies focus on reducing symptoms but fail to restore existing structural
damage. Mesenchymal stromal cell (MSC) administration can ameliorate airway …
damage. Mesenchymal stromal cell (MSC) administration can ameliorate airway …
Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection
Dengue fever is an emerging viral disease transmitted by arthropods to humans in tropical
countries. Dengue hemorrhagic fever (DHF) is escalating in frequency and mortality rates …
countries. Dengue hemorrhagic fever (DHF) is escalating in frequency and mortality rates …
[HTML][HTML] The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF)
F Varyani, S Löser, KJ Filbey, Y Harcus, C Drurey… - Mucosal …, 2022 - Elsevier
Macrophage migration inhibitory factor (MIF) is a key innate immune mediator with
chemokine-and cytokine-like properties in the inflammatory pathway. While its actions on …
chemokine-and cytokine-like properties in the inflammatory pathway. While its actions on …
Advances and insights for small molecule inhibition of macrophage migration inhibitory factor
V Trivedi-Parmar, WL Jorgensen - Journal of medicinal chemistry, 2018 - ACS Publications
Macrophage migration inhibitory factor (MIF) is an upstream regulator of the immune
response whose dysregulation is tied to a broad spectrum of inflammatory and proliferative …
response whose dysregulation is tied to a broad spectrum of inflammatory and proliferative …
Blockade of MIF biological activity ameliorates house dust mite‐induced allergic airway inflammation in humanized MIF mice
H Dunbar, IJ Hawthorne, C Tunstead… - The FASEB …, 2023 - mural.maynoothuniversity.ie
Macrophage migration inhibitory factor (MIF) expression is controlled by a functional
promoter polymorphism, where the number of tetranucleotide repeats (CATTn) corresponds …
promoter polymorphism, where the number of tetranucleotide repeats (CATTn) corresponds …
The role of MIF in chronic lung diseases: looking beyond inflammation
L Florez-Sampedro, A Soto-Gamez… - … of Physiology-Lung …, 2020 - journals.physiology.org
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that has been
associated with many diseases. Most studies found in literature describe MIF as a …
associated with many diseases. Most studies found in literature describe MIF as a …
Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+ CD25+ Foxp3+ T cell …
SK Park, MK Cho, HK Park, KH Lee, SJ Lee… - The Journal of …, 2009 - journals.aai.org
We have cloned the macrophage migration inhibitory factor (MIF)-like protein (Anisakis
simplex (As)-MIF) from larvae of the whale worm (Anisakis simplex third-stage larvae) …
simplex (As)-MIF) from larvae of the whale worm (Anisakis simplex third-stage larvae) …
The MIF antagonist ISO-1 attenuates corticosteroid-insensitive inflammation and airways hyperresponsiveness in an ozone-induced model of COPD
KE Russell, KF Chung, CJ Clarke, AL Durham… - PLoS …, 2016 - journals.plos.org
Introduction Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine
associated with acute and chronic inflammatory disorders and corticosteroid insensitivity. Its …
associated with acute and chronic inflammatory disorders and corticosteroid insensitivity. Its …