Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million …

Parasitic diseases such as malaria, leishmaniasis, and trypanosomiasis represent a
significant global burden and pose a great challenge to drug discovery and delivery …

Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …

Neglected tropical disease (NTD) is a set of 20 deadliest endemic diseases which shows its
presence in most of the developing countries worldwide. Nearly 1 billion of the population …

Introduction: A century after its discovery, American trypanosomiasis or Chagas disease
remains a serious health problem in Latin America, where it affects around 7–8 million …

Chagas disease is a neglected parasitic infection caused by the protozoan Trypanosoma
cruzi. After a mostly clinically silent acute phase, the disease becomes a lifelong chronic …

Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Benznidazole and nifurtimox are the two approved drugs for their treatment, but both …

Hundred years after the discovery of Chagas' disease, there is a lack of effective treatment to
control this neglected disease caused by the parasite Trypanosoma cruzi. The transmission …

Over several thousand years, the flagellated Trypanosome cruzi–causative agent of Chagas
disease–developed a complex life cycle between the reduviidae vectors and its human …

Chagas disease is one of the most important public health problems in Latin America due to
its high mortality and morbidity levels. There is no effective treatment for this disease since …