Dendritic protein synthesis in the normal and diseased brain
SA Swanger, GJ Bassell - Neuroscience, 2013 - Elsevier
Synaptic activity is a spatially limited process that requires a precise, yet dynamic,
complement of proteins within the synaptic micro-domain. The maintenance and regulation …
complement of proteins within the synaptic micro-domain. The maintenance and regulation …
Revisiting the development of cerebellar inhibitory interneurons in the light of single-cell genetic analyses
K Schilling - Histochemistry and Cell Biology, 2024 - Springer
The present review aims to provide a short update of our understanding of the inhibitory
interneurons of the cerebellum. While these cells constitute but a minority of all cerebellar …
interneurons of the cerebellum. While these cells constitute but a minority of all cerebellar …
Digital expression profiling of the compartmentalized translatome of Purkinje neurons
A Kratz, P Beguin, M Kaneko, T Chimura… - Genome …, 2014 - genome.cshlp.org
Underlying the complexity of the mammalian brain is its network of neuronal connections,
but also the molecular networks of signaling pathways, protein interactions, and regulated …
but also the molecular networks of signaling pathways, protein interactions, and regulated …
In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
Fluorescent staining of newly transcribed RNA via metabolic labelling with 5-ethynyluridine
(EU) and click chemistry enables visualisation of changes in transcription, such as in …
(EU) and click chemistry enables visualisation of changes in transcription, such as in …
Sensorimotor enhancement in mouse mutants lacking the Purkinje cell-specific Gi/o modulator, Pcp2 (L7)
E Iscru, Y Serinagaoglu, K Schilling, J Tian… - Molecular and Cellular …, 2009 - Elsevier
Pcp2 (L7) is a GoLoco domain protein specifically and abundantly expressed in cerebellar
Purkinje cells. It has been hypothesized to “tune” Gi/o-coupled receptor modulation of …
Purkinje cells. It has been hypothesized to “tune” Gi/o-coupled receptor modulation of …
Developmental upregulation of an alternative form of pcp2 with reduced GDI activity
JJ Barski, BM Denker, J Guan, M Lauth, F Spreafico… - The Cerebellum, 2014 - Springer
The pcp2/L7 gene is characterized by its very cell type-specific expression restricted to
cerebellar Purkinje cells and retinal bipolar neurons. Although remarkable progress as to …
cerebellar Purkinje cells and retinal bipolar neurons. Although remarkable progress as to …