Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

meso-Methyl BODIPY Photocages: Mechanisms, Photochemical Properties, and Applications

P Shrestha, D Kand, R Weinstain… - Journal of the American …, 2023 - ACS Publications
meso-methyl BODIPY photocages have recently emerged as an exciting new class of
photoremovable protecting groups (PPGs) that release leaving groups upon absorption of …

Dynamics of excitons in conjugated molecules and organic semiconductor systems

OP Dimitriev - Chemical Reviews, 2022 - ACS Publications
The exciton, an excited electron–hole pair bound by Coulomb attraction, plays a key role in
photophysics of organic molecules and drives practically important phenomena such as …

Emerging strategies in stimuli-responsive prodrug nanosystems for cancer therapy

C Ding, C Chen, X Zeng, H Chen, Y Zhao - ACS nano, 2022 - ACS Publications
Prodrugs are chemically modified drug molecules that are inactive before administration.
After administration, they are converted in situ to parent drugs and induce the mechanism of …

Basic structural modifications for improving the practical properties of BODIPY

NA Bumagina, EV Antina, AA Ksenofontov… - Coordination Chemistry …, 2022 - Elsevier
The review considers the results of research by scientists from different countries in the field
of synthesis and photophysical property study of known BODIPY. We focus on describing the …

A Near‐Infrared Light‐Activated Photocage Based on a Ruthenium Complex for Cancer Phototherapy

G He, M He, R Wang, X Li, H Hu… - Angewandte Chemie …, 2023 - Wiley Online Library
Conventional photocages only respond to short wavelength light, which is a significant
obstacle to developing efficient phototherapy in vivo. The development of photocages …

Stimulus-cleavable chemistry in the field of controlled drug delivery

Y Xue, H Bai, B Peng, B Fang, J Baell, L Li… - Chemical Society …, 2021 - pubs.rsc.org
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Biofilm heterogeneity-adaptive photoredox catalysis enables red light-triggered nitric oxide release for combating drug-resistant infections

J Cheng, G Gan, S Zheng, G Zhang, C Zhu… - Nature …, 2023 - nature.com
The formation of biofilms is closely associated with persistent and chronic infections, and
physiological heterogeneity such as pH and oxygen gradients renders biofilms highly …

Bioorthogonal chemistry for prodrug activation in vivo

Q Fu, S Shen, P Sun, Z Gu, Y Bai, X Wang… - Chemical Society …, 2023 - pubs.rsc.org
Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

Plasmon‐driven catalytic chemotherapy augments cancer immunotherapy through induction of immunogenic cell death and blockage of IDO pathway

Y Ding, Z Sun, Y Gao, S Zhang, C Yang… - Advanced …, 2021 - Wiley Online Library
Clinical trials confirm the combination of indoleamine 2, 3‐dioxygenase (IDO) blockade and
immunogenic chemotherapy represents a brilliant future in cancer therapy. However, it …