Advances in biomaterials and the need for patient-specific bone scaffolds require modern
manufacturing approaches in addition to a design strategy. Hybrid materials such as those …

Osteochondral defects are caused by injury to both the articular cartilage and subchondral
bone within skeletal joints. They can lead to irreversible joint damage and increase the risk …

Cell-based therapies are a promising alternative to grafts and organ transplantation for
treating tissue loss or damage due to trauma, malfunction, or disease. Over the past two …

Poly (l-lactide-co-caprolactone)(PLCL, 50: 50) has been used in cartilage tissue engineering
because of its high elasticity. However, its mechanical properties, including its rigidity and …

Articular cartilage (AC) has a very limited intrinsic repair capacity after injury or disease.
Although exogenous cell-based regenerative approaches have obtained acceptable …

The main aim of this study was to examine the stability of a range of polyethyleneglycol
dimethacrylate (PEGDMA) hydrogels over a 28-day period in simulated physiological …

The choice of the best-suited cell population for the regeneration of damaged or diseased
cartilage depends on the effectiveness of culture conditions (eg media supplements, three …

Articular cartilage is a mechanically and structurally complex, lubricious tissue that permits
load-bearing and frictionless movement of our joints upon articulation. Unfortunately …

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Articular osteochondral (OC) defects are a global clinical problem characterized by loss of
full-thickness articular cartilage with underlying calcified cartilage through to the …