[HTML][HTML] Reciprocal regulation of mesenchymal stem cells and immune responses
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …
attention as a way to better mimic the complex interactions between individual cells and the …
Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects
M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
Three-dimensional spheroid culture of human mesenchymal stem cells: offering therapeutic advantages and in vitro glimpses of the in vivo state
BL Yen, CC Hsieh, PJ Hsu, CC Chang… - Stem cells …, 2023 - academic.oup.com
As invaluable as the standard 2-dimensional (2D) monolayer in vitro cell culture system has
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
[HTML][HTML] Different priming strategies improve distinct therapeutic capabilities of mesenchymal stromal/stem cells: Potential implications for their clinical use
Mesenchymal stromal/stem cells (MSCs) have shown significant therapeutic potential, and
have therefore been extensively investigated in preclinical studies of regenerative medicine …
have therefore been extensively investigated in preclinical studies of regenerative medicine …
[HTML][HTML] Mesenchymal stromal/stem cells spheroid culture effect on the therapeutic efficacy of these cells and their exosomes: A new strategy to overcome cell therapy …
Cell therapy is one of the new treatment methods in which mesenchymal stem/stromal cell
(MSCs) transplantation is one of the cells widely used in this field. The results of MSCs …
(MSCs) transplantation is one of the cells widely used in this field. The results of MSCs …
Multisized photoannealable microgels regulate cell spreading, aggregation, and macrophage phenotype through microporous void space
JM Lowen, GC Bond, KH Griffin… - Advanced …, 2023 - Wiley Online Library
Microgels are an emerging platform for in vitro models and guiding cell fate due to their
inherent porosity and tunability. This work describes a light‐based technique for rapidly …
inherent porosity and tunability. This work describes a light‐based technique for rapidly …
[HTML][HTML] Engineering exosomes by three-dimensional porous scaffold culture of human umbilical cord mesenchymal stem cells promote osteochondral repair
Z Yan, H Yin, J Wu, G Tian, M Li, Z Liao, S He… - Materials Today Bio, 2023 - Elsevier
Improving the poor microenvironment in the joint cavity has potential for treating cartilage
injury, and mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos), which can …
injury, and mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos), which can …
Therapeutic perspectives for inflammation and senescence in osteoarthritis using mesenchymal stem cells, mesenchymal stem cell-derived extracellular vesicles and …
MG Rizzo, TM Best, J Huard, M Philippon, F Hornicek… - Cells, 2023 - mdpi.com
Osteoarthritis (OA) is the most common cause of disability worldwide among the elderly.
Alarmingly, the incidence of OA in individuals less than 40 years of age is rising, likely due to …
Alarmingly, the incidence of OA in individuals less than 40 years of age is rising, likely due to …
Mesenchymal stem cell-based therapy for non-healing wounds due to chronic limb-threatening ischemia: a review of preclinical and clinical studies
CT Huerta, FA Voza, YY Ortiz, ZJ Liu… - Frontiers in …, 2023 - frontiersin.org
Progressive peripheral arterial disease (PAD) can result in chronic limb-threatening
ischemia (CLTI) characterized by clinical complications including rest pain, gangrene and …
ischemia (CLTI) characterized by clinical complications including rest pain, gangrene and …