mTOR-Rictor-EGFR axis in oncogenesis and diagnosis of glioblastoma multiforme

MJ Ramaiah, KR Kumar - Molecular Biology Reports, 2021 - Springer
Glioblastoma multiforme (GBM) is one of the aggressive brain cancers with patients having
less survival period upto 12–15 months. Mammalian target of rapamycin (mTOR) is a …

[HTML][HTML] Bidirectional relation between parkinson's disease and glioblastoma multiforme

P Mencke, Z Hanss, I Boussaad, PE Sugier… - Frontiers in …, 2020 - frontiersin.org
Cancer and Parkinson's disease (PD) define two disease entities that include opposite
concepts. Indeed, the involved mechanisms are at different ends of a spectrum related to cell …

[HTML][HTML] The pyroptosis mediated biomarker pattern: an emerging diagnostic approach for Parkinson's disease

J Liang, Z Wan, C Qian, M Rasheed, C Cao… - Cellular & Molecular …, 2024 - Springer
Background Parkinson's disease (PD) affects 1% of people over 60, and long-term levodopa
treatment can cause side effects. Early diagnosis is of great significance in slowing down the …

[HTML][HTML] Identification of hub genes and small-molecule compounds in medulloblastoma by integrated bioinformatic analyses

Z Liu, R Zhang, Z Sun, J Yao, P Yao, X Chen, X Wang… - PeerJ, 2020 - peerj.com
Background Medulloblastoma (MB) is the most common intracranial malignant tumor in
children. The genes and pathways involved in the pathogenesis of MB are relatively …

Metabolic wastes are extracellularly disposed by excretosomes, nanotubes and exophers in mouse HT22 cells through an autophagic vesicle clustering mechanism

H Fu, J Li, P Du, W Jin, D Cui - bioRxiv, 2019 - biorxiv.org
Neurodegenerative diseases are characterized by metabolic waste accumulations in
neuronal cells. However, little is known about the mechanism of metabolic waste disposal …

Role of mitochondrial reactive oxygen species in glioblastoma drug resistance and strategies for therapeutic intervention

AL Dico, D Salvatore, C Diceglie, C Martelli… - … and Innovative Reversal …, 2021 - Elsevier
Glioblastoma (GBM) is the most aggressive tumor of CNS characterized by a poor prognosis
mainly due to the resistance to the available treatments. Temozolomide (TMZ) is the gold …

[PDF][PDF] Metabolic wastes are removed by excretosomes, nanotubes and exophers in mouse HT22 cells through an autophagic vesicle clustering mechanism

H Fu, J Li, P Du, W Jin, D Cui - bioRxiv, 2019 - biorxiv.org
Neurodegenerative diseases are characterized by metabolic waste accumulations in
neuronal cells. However, little is known about the mechanism of metabolic waste disposal …

HIGH RESOLUTION MASS SPECTROMETRY WITH CHIP-BASED IONIZATION FOR THE ASSESSMENT OF NONCOVALENT INTERACTIONS OF PROTEINS WITH …

ICÄ Raluca, M SÂRBU, AD ZAMFIR - Scientific and Technical Bulletin, Series …, 2020 - uav.ro
The noncovalent interactions between the amyloid beta (Aβ) and α-synuclein (Syn) proteins
with native gangliosides extracted and purified from human brain and human glioma were …