Advances in research on type 2 diabetes mellitus targets and therapeutic agents

J Su, Y Luo, S Hu, L Tang, S Ouyang - International Journal of Molecular …, 2023 - mdpi.com
Diabetes mellitus is a chronic multifaceted disease with multiple potential complications, the
treatment of which can only delay and prolong the terminal stage of the disease, ie, type 2 …

Sarcopenia and diabetes: A detrimental liaison of advancing age

G Lisco, OE Disoteo, A De Tullio, V De Geronimo… - Nutrients, 2023 - mdpi.com
Sarcopenia is an age-related clinical complaint characterized by the progressive
deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is …

Gender-specific risk factors and prevalence for sarcopenia among community-dwelling young-old adults

J Hwang, S Park - International Journal of Environmental Research and …, 2022 - mdpi.com
Sarcopenia in the elderly is a serious global public health problem. Numerous sarcopenia
studies classified their subjects into a single group, but health conditions and body …

Gender-specific prevalence and risk factors of sarcopenic obesity in the Korean elderly population: a nationwide cross-sectional study

J Hwang, S Park - International Journal of Environmental Research and …, 2023 - mdpi.com
Sarcopenic obesity (SO) is characterized by the combination of sarcopenia and obesity. This
study evaluates the gender-specific prevalence of SO and examines the identified gender …

A Korean Nationwide Cross-Sectional Study Investigating Risk Factors, Prevalence, and Characteristics of Sarcopenia in Men in Early Old Age

J Hwang, S Park - Healthcare, 2023 - mdpi.com
The present study investigated the risk factors, prevalence, and characteristics of sarcopenia
among men aged 50–64 years. A total of 2868 participants were enrolled in this study. Of …

Sarcopenia in a type 2 diabetic state: reviewing literature on the pathological consequences of oxidative stress and inflammation beyond the neutralizing effect of …

N Muvhulawa, SE Mazibuko-Mbeje, D Ndwandwe… - Life Sciences, 2023 - Elsevier
Sarcopenia remains one of the major pathological features of type 2 diabetes (T2D),
especially in older individuals. This condition describes gradual loss of muscle mass …

Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats

NR Kerr, CW Mossman, CH Chou… - Journal of Applied …, 2024 - journals.physiology.org
Alzheimer's disease (AD) is the fifth leading cause of death in older adults, and treatment
options are severely lacking. Recent findings demonstrate a strong relationship between …

Effect of Carica papaya on IRS-1/Akt Signaling Mechanisms in High-Fat-Diet–Streptozotocin-Induced Type 2 Diabetic Experimental Rats: A Mechanistic Approach

JR Roy, CS Janaki, S Jayaraman, V Periyasamy… - Nutrients, 2022 - mdpi.com
Despite rigorous endeavors, existing attempts to handle type 2 diabetes (T2DM) are still a
long way off, as a substantial number of patients do not meet therapeutic targets. Insulin …

Combine Therapy of Gallic Acid and Allicin in Management of Diabetes

R Kumar, P Sood, V Rana… - Journal for Research …, 2023 - jrasb.stallionpublication.com
Type 2 diabetes, also known (DM) is a metabolic disorder with a high mortality and disability
incidence. The development and activation of oxidative stress (OS) are crucial to the …

Exploring incidence and potential risk factors of sarcopenic obesity among middle-aged women residing in a community

J Hwang, IY Moon - Journal of the Korean Society of Physical …, 2023 - koreascience.kr
PURPOSE: This study evaluated the incidence of sarcopenic obesity (SO) and examined the
specific risk factors in a community-dwelling middle-aged population of women. METHODS …