Herpes simplex virus-1 in the brain: the dark side of a sneaky infection

ME Marcocci, G Napoletani, V Protto, O Kolesova… - Trends in …, 2020 - cell.com
Herpes simplex virus-1 (HSV-1) establishes latency preferentially in sensory neurons of
peripheral ganglia. A variety of stresses can induce recurrent reactivations of the virus …

Herpes keratitis

AM Rowe, AJS Leger, S Jeon, DK Dhaliwal… - Progress in retinal and …, 2013 - Elsevier
Herpes simplex virus-1 (HSV-1) infects the majority of the world's population. These
infections are often asymptomatic, but ocular HSV-1 infections cause multiple pathologies …

Gene therapy tools for brain diseases

S Ingusci, G Verlengia, M Soukupova… - Frontiers in …, 2019 - frontiersin.org
Neurological disorders affecting the central nervous system (CNS) are still incompletely
understood. Many of these disorders lack a cure and are seeking more specific and effective …

The molecular basis of herpes simplex virus latency

MP Nicoll, JT Proença… - FEMS microbiology …, 2012 - academic.oup.com
Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within
sensory neurones. Following primary infection, the virus replicates productively within …

Occult HBV infection

G Raimondo, T Pollicino - Hepatitis B virus in human diseases, 2016 - Springer
The long-lasting persistence of HBV genomes in the liver (and in some cases also in the
serum) of HBsAg negative subjects is termed occult HBV infection (OBI). This peculiar …

PPARγ and Wnt signaling in adipogenic and osteogenic differentiation of mesenchymal stem cells

Z Yuan, Q Li, S Luo, Z Liu, D Luo… - Current stem cell …, 2016 - ingentaconnect.com
Mesenchymal stem cells (MSCs) arise from a variety of tissues, including bone marrow and
adipose tissue and, accordingly, have the potential to differentiate into multiple cell types …

A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation

PGE Kennedy, J Rovnak… - Journal of General …, 2015 - microbiologyresearch.org
Herpes simplex virus type 1 (HSV-1; human herpesvirus 1) and varicella-zoster virus (VZV;
human herpesvirus 3) are human neurotropic alphaherpesviruses that cause lifelong …

Herpesviruses: harmonious pathogens but relevant cofactors in other diseases?

S Sehrawat, D Kumar, BT Rouse - Frontiers in cellular and infection …, 2018 - frontiersin.org
Most vertebrates are infected with one or more herpesviruses and remain so for the rest of
their lives. The relationship of immunocompetent healthy host with herpesviruses may …

Epigenetics and genetics of viral latency

PM Lieberman - Cell host & microbe, 2016 - cell.com
Viral latency can be considered a metastable, nonproductive infection state that is capable
of subsequent reactivation to repeat the infection cycle. Viral latent infections have …

Update on herpes virus infections of the nervous system

I Steiner, F Benninger - Current neurology and neuroscience reports, 2013 - Springer
Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) are human neurotropic viruses
that establish latent infection in dorsal root ganglia (DRG) for the entire life of the host. From …