Salivary gland function, development, and regeneration
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …
and overall health. Understanding both the unique structure and physiological function of …
[HTML][HTML] Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions
KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …
head and neck, leading to complications, including mucositis, xerostomia and …
Low-level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 2: proposed applications and …
JAEM Zecha, JE Raber-Durlacher, RG Nair… - Supportive Care in …, 2016 - Springer
Purpose There is a large body of evidence supporting the efficacy of low-level laser therapy
(LLLT), more recently termed photobiomodulation (PBM) for the management of oral …
(LLLT), more recently termed photobiomodulation (PBM) for the management of oral …
Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers
A Vissink, JB Mitchell, BJ Baum, KH Limesand… - International Journal of …, 2010 - Elsevier
The most significant long-term complication of radiotherapy in the head-and-neck region is
hyposalivation and its related complaints, particularily xerostomia. This review addresses …
hyposalivation and its related complaints, particularily xerostomia. This review addresses …
Salivary gland hypofunction and xerostomia in head and neck radiation patients
SB Jensen, A Vissink, KH Limesand… - JNCI …, 2019 - academic.oup.com
Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …
[HTML][HTML] The salivary glands as a dose limiting organ of PSMA-targeted radionuclide therapy: a review of the lessons learnt so far
N Heynickx, K Herrmann, K Vermeulen… - Nuclear medicine and …, 2021 - Elsevier
At present, prostate cancer remains the second most occurring cancer in men, in Europe.
Treatment efficacy for therapy of advanced metastatic disease, and metastatic castration …
Treatment efficacy for therapy of advanced metastatic disease, and metastatic castration …
Salivary hypofunction: an update on aetiology, diagnosis and therapeutics
J Saleh, MAZ Figueiredo, K Cherubini, FG Salum - Archives of oral biology, 2015 - Elsevier
Saliva is of paramount importance for the maintenance of oral and general homeostasis.
Salivary hypofunction predispose patients to disorders such as dysgeusia, pain and burning …
Salivary hypofunction predispose patients to disorders such as dysgeusia, pain and burning …
Sensitivity of salivary glands to radiation: from animal models to therapies
O Grundmann, GC Mitchell… - Journal of dental …, 2009 - journals.sagepub.com
Radiation therapy for head and neck cancer causes significant secondary side-effects in
normal salivary glands, resulting in diminished quality of life for these individuals. Salivary …
normal salivary glands, resulting in diminished quality of life for these individuals. Salivary …
[HTML][HTML] Autologous mesenchymal stem cells offer a new paradigm for salivary gland regeneration
M Marinkovic, ON Tran, H Wang… - International Journal of …, 2023 - nature.com
Salivary gland (SG) dysfunction, due to radiotherapy, disease, or aging, is a clinical
manifestation that has the potential to cause severe oral and/or systemic diseases and …
manifestation that has the potential to cause severe oral and/or systemic diseases and …
Salivary glands regenerate after radiation injury through SOX2‐mediated secretory cell replacement
E Emmerson, AJ May, L Berthoin… - EMBO molecular …, 2018 - embopress.org
Salivary gland acinar cells are routinely destroyed during radiation treatment for head and
neck cancer that results in a lifetime of hyposalivation and co‐morbidities. A potential …
neck cancer that results in a lifetime of hyposalivation and co‐morbidities. A potential …