Distributions of the HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 alleles and haplotype frequencies of 1763 stem cell donors in the Colombian Bone Marrow …

DG Hernández-Mejía, IA Páez-Gutiérrez… - Frontiers in …, 2023 - frontiersin.org
The HLA compatibility continues to be the main limitation when finding compatible donors,
especially if an identical match is not found within the patient's family group. The creation of …

CD8+ T-cell response to mutated HLA-B* 35-restricted Gag HY9 and HA9 epitopes from HIV-1 variants from Medellin, Colombia

A Sánchez-Martínez, SG Hoyos, JC Alzate-Ángel… - Heliyon, 2024 - cell.com
The HLA-B* 35 alleles have been associated with a slow or rapid progression of HIV-1
infection. However, the mechanisms related to HIV-1 progression have yet to be entirely …

HLA-B allele, genotype, and haplotype frequencies in a group of healthy individuals in Colombia

C Romero-Sánchez, N Hernández… - JCR: Journal of …, 2021 - journals.lww.com
Background The sequencing of alleles of the HLA-B, a human leukocyte antigen (HLA) class
I gene, was established as the most polymorphic of chromosome 6 and of the entire human …

Functional Profile of CD8+ T-Cells in Response to HLA-A*02:01-Restricted Mutated Epitopes Derived from the Gag Protein of Circulating HIV-1 Strains from Medellín …

A Sánchez-Martínez, L Acevedo-Sáenz… - Frontiers in …, 2022 - frontiersin.org
CD8+ T-cells play a crucial role in the control of HIV replication. HIV-specific CD8+ T-cell
responses rapidly expand since the acute phase of the infection, and it has been observed …

Using next‐generation sequencing for characterising HLA‐DRB1 and DQB1 loci in a cohort of Colombian women

L Del Río‐Ospina, M Camargo, SC Soto‐De León… - HLA, 2019 - Wiley Online Library
The Colombian population is characterised by a high genetic diversity, secondary to the
ethnic mixture arising from colonisation. Unfortunately, few reports are available regarding …

Polimorfismo de los antígenos leucocitarios humanos en receptores cubanos de trasplante relacionado de progenitores hematopoyéticas

JS Burón Hernández, OM de la Guardia Peña… - Revista Cubana de …, 2019 - scielo.sld.cu
Introducción: El trasplante relacionado de células progenitoras hematopoyéticas (TCPH) es
una alternativa terapéutica curativa para los pacientes con ciertos tipos de hemopatías o de …

Polymorphism of human leukocyte antigens in Cuban recipients of related hematopoietic stem cell transplants

JSB Hernández, OM de la Guardia Peña… - Revista Cubana de …, 2019 - medigraphic.com
Introduction: Related hematopoietic progenitor cell (TCPH) transplantation is a curative
therapeutic alternative for patients with certain types of hemopathies or immunodeficiencies …

Asociación de los alelos de HLA con la persistencia, depuración y reinfección de tipos de Virus del Papiloma Humano de alto riesgo

LF Del Río Ospina - 2019 - repositorio.unal.edu.co
Este trabajo tuvo como objetivo identificar los alelos y haplotipos HLA-DRB1 y DQB1
relacionados con la persistencia, depuración y redetección de 6 tipos de VPH de alto riesgo …

Frecuencia Alélica Y Genotipica De Hla-B Y Hla-B* 27 En Un Grupo De Individuos Sanos En Colombia

NA Hernández Bocanegra - 2019 - repositorio.unicolmayor.edu.co
Varios de los genes de la respuesta inmune se encuentran en el complejo mayor de
histocompatibilidad (MHC). El sistema de antígenos de leucocitos humanos (HLA) es un …