Chlorine is one of the most common atoms present in small-molecule drugs beyond carbon,
hydrogen, nitrogen, and oxygen. There are currently more than 250 FDA-approved chlorine …

Conspectus Interactions between sterically crowded hydrocarbon-substituted ligands are
widely considered to be repulsive because of the intrusion of the electron clouds of the …

We report a highly enantioselective radical-based hydroamination of enol esters with
sulfonamides jointly catalyzed by an Ir photocatalyst, Brønsted base, and tetrapeptide thiol …

Conspectus Alkanes play a pivotal role in industrial, environmental, and biological
processes. They are characterized by their carbon–carbon single-bond structure …

London dispersion (LD) interactions are the main contribution of the attractive part of the van
der Waals potential. Even though LD effects are the driving force for molecular aggregation …

London dispersion (LD) is attracting more and more attention in catalysis since LD is
ubiquitously present and cumulative. Since dispersion is hard to grasp, recent research has …

Conspectus London forces constitute an attractive component of van der Waals interactions
and originate from transient correlated momentary dipoles in adjacent atoms. The in-depth …

“Soft theories,” ie,“heuristic models based on reasoning by analogy” largely drove chemistry
understanding for 150 years or more. But soft theories have their limitations and with the …

Anionic ligands containing a nonbonded lone pair (ie, amido, thiolate) are well-known to
cooperate with a metal center in bifunctional catalytic reactions. An NHC CoII (κ3-SNS) …

We report an evaluation of the importance of London dispersion in moderately large (up to
36 heavy atoms) organic molecules by means of a molecular torsion balance whose …