mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …

RNA interference (RNAi) is a specific gene‐silencing mechanism triggered by small
interfering RNA (siRNA). The application of RNAi in the clinic requires the development of …

Near-infrared light-responsive inorganic nanoparticles have been shown to enhance the
efficacy of cancer photothermal ablation therapy. However, current nanoparticle-mediated …

The synthesis of multifunctional magnetic nanoparticles (NPs) is a highly active area of
current research located at the interface between materials science, biotechnology and …

Purpose: Stimulation of toll-like receptor-9 (TLR9) by CpG oligodeoxynucleotides (CpG) has
been shown to counteract the immunosuppressive microenvironment and to inhibit tumor …

There is an urgent need for new strategies to combat infectious diseases in developing
countries. Many pathogens have evolved to elude immunity and this has limited the utility of …

Dendritic cells (DCs) are potent antigen-presenting cells that possess the ability to stimulate
naïve T cells. Antigen presentation by mature (activated) DCs is a prerequisite for the …

The specific activation of Toll-like receptors (TLRs) has potential utility for a variety of
therapeutic indications including antiviral immunotherapy and as vaccine adjuvants. TLR7 …

In this work, multifunctional lipid nanocapsules (M-LNC) were designed to combine the
activity of the cytotoxic drug paclitaxel (PTX) with the immunostimulant CpG. This …

As a result of their unique physical properties, biological membrane mimetics, such as
liposomes, are used in a broad range of scientific and technological applications …