Drug delivery is a growing field of interdisciplinary activities that combine the use of new
materials with the biochemical properties of selected drugs, with the aim of improving their …

CHAIR: Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA TASK FORCE 1:
Dipchand A: Hospital for Sick Children, Toronto Ontario, Canada; Starling R: Cleveland …

This review seeks to apply a decision-making algorithm to establish whether clinical
pharmacokinetic monitoring (CPM) of sirolimus (rapamycin) in solid organ transplantation is …

Pancreatic islet transplantation has the potential to be an effective treatment for type 1
diabetes mellitus. While recent improvements have improved 1-year outcomes, follow-up …

Cyclosporine A (CsA) and tacrolimus (also known as FK506) are natural compounds with
immunosuppressive activity that have improved the outcome of organ transplantation …

Tipranavir is a nonpeptidic protease inhibitor that has activity against human
immunodeficiency virus strains resistant to multiple protease inhibitors. Tipranavir 500 mg is …

In the present paper we describe an atomic force microscopy (AFM)-based method for the
quantitative analysis of FK506 (Tacrolimus) in whole blood (WB) samples. Current reference …

Tacrolimus and sirolimus are important immunosuppressive drugs used in human islet
transplantation; however, they are linked to detrimental effects on islets and reduction of …

The narrow therapeutic window of tacrolimus necessitates daily monitoring and predictive
algorithms based on genetic and nongenetic factors. In this study, we constructed predictive …

BACKGROUND: Tacrolimus is a macrolide immunosuppressant indicated for prophylaxis of
transplant rejection. The European regulatory authorities require comparative bioavailability …