Diverse macrophage populations mediate acute lung inflammation and resolution

NR Aggarwal, LS King… - American Journal of …, 2014 - journals.physiology.org
Acute respiratory distress syndrome (ARDS) is a devastating disease with distinct
pathological stages. Fundamental to ARDS is the acute onset of lung inflammation as a part …

MSCs and inflammatory cells crosstalk in regenerative medicine: concerted actions for optimized resolution driven by energy metabolism

V Planat-Benard, A Varin, L Casteilla - Frontiers in immunology, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are currently widely used in cell based therapy
regarding to their remarkable efficacy in controlling the inflammatory status in patients …

Wnt signaling modulates macrophage polarization and is regulated by biomaterial surface properties

JO Abaricia, AH Shah, M Chaubal, KM Hotchkiss… - Biomaterials, 2020 - Elsevier
Macrophages are among the first cells to interact with biomaterials and ultimately determine
their integrative fate. Biomaterial surface characteristics like roughness and hydrophilicity …

Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages

TS Rajan, S Giacoppo, R Iori, GR De Nicola, G Grassi… - Fitoterapia, 2016 - Elsevier
Inflammatory response plays an important role in the activation and progress of many
debilitating diseases. Natural products, like cannabidiol, a constituent of Cannabis sativa …

Klebsiella pneumoniae infection of murine neutrophils impairs their efferocytic clearance by modulating cell death machinery

CN Jondle, K Gupta, BB Mishra, J Sharma - PLoS pathogens, 2018 - journals.plos.org
Neutrophils are the first infiltrating cell type essential for combating pneumoseptic infections
by bacterial pathogens including Klebsiella pneumoniae (KPn). Following an infection or …

Macrophages: the potent immunoregulatory innate immune cells

V Kumar - Macrophage Activation-Biology and Disease, 2019 - books.google.com
Macrophages are ubiquitously present innate immune cells in humans and animals
belonging to both invertebrates and vertebrates. These cells were first recognized by Elia …

Advanced age alters monocyte and macrophage responses

JM Albright, RC Dunn, JA Shults, DM Boe… - Antioxidants & redox …, 2016 - liebertpub.com
Significance: With the growing population of baby boomers, there is a great need to
determine the effects of advanced age on the function of the immune system. Recent …

A novel strategy for treating inflammatory bowel disease by targeting delivery of methotrexate through glucan particles

Y Sun, B Duan, H Chen, X Xu - Advanced Healthcare Materials, 2020 - Wiley Online Library
Therapy of inflammatory bowel disease (IBD) has been a difficult task in the medical field.
There is a great clinical need for more effective treatments for IBD. Herein, a targeted oral …

Zoledronic acid exacerbates inflammation through M1 macrophage polarization

J Kaneko, T Okinaga, H Hikiji, W Ariyoshi… - Inflammation and …, 2018 - Springer
Abstract Background Zoledronic acid (Zol), one of the bisphosphonates, is frequently utilized
for the treatment of osteoporosis and bone metastasis. However, the onset of medication …

[PDF][PDF] An endoplasmic reticulum protein, Nogo‐B, facilitates alcoholic liver disease through regulation of kupffer cell polarization

JK Park, M Shao, MY Kim, SK Baik, MY Cho… - …, 2017 - Wiley Online Library
Nogo‐B (Reticulon 4B) is an endoplasmic reticulum (ER) resident protein that regulates ER
structure and function. Because ER stress is known to induce M2 macrophage polarization …