The human immunodeficiency virus: infectivity and mechanisms of pathogenesis

AS Fauci - Science, 1988 - science.org
Infection with the human immunodeficiency virus (HIV) results in a profound
immunosuppression due predominantly to a selective depletion of helper/inducer T …

AIDS: an international perspective

P Piot, FA Plummer, FS Mhalu, JL Lamboray, J Chin… - Science, 1988 - science.org
The acquired immunodeficiency syndrome (AIDS) and infection with the human
immunodeficiency virus type 1 (HIV-1) constitute a worldwide public health problem …

Isolation of a new human retrovirus from West African patients with AIDS

F Clavel, D Guétard, F Brun-Vézinet, S Chamaret… - Science, 1986 - science.org
The etiological agent of AIDS, LAV/HTLV-III, is common in Central Africa but is not endemic
in other areas of that continent. A novel human retrovirus, distinct from LAV/HTLV-III, has …

Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders

SZ Salahuddin, DV Ablashi, PD Markham, SF Josephs… - Science, 1986 - science.org
A novel human B-lymphotropic virus (HBLV) was isolated from the peripheral blood
leukocytes of six individuals: two HTLV-III seropositive patients from the United States (one …

Genome organization and transactivation of the human immunodeficiency virus type 2

M Guyader, M Emerman, P Sonigo, F Clavel… - Nature, 1987 - nature.com
Abstract Analysis of the nucleotide sequence of the human retrovirus associated with AIDS
in West Africa, HIV-2, shows that it is evolutionary distant from the previously characterized …

Molecular cloning and polymorphism of the human immune deficiency virus type 2

F Clavel, M Guyader, D Guétard, M Sallé, L Montagnier… - Nature, 1986 - nature.com
We recently reported the isolation of a novel retrovirus, the human immune deficiency virus
type 2 (HIV-2, previously named LAV-2), from patients with acquired immune deficiency …

AIDS in Africa: an epidemiologic paradigm

TC Quinn, JM Mann, JW Curran, P Piot - Science, 1986 - science.org
Cases of the acquired immune deficiency syndrome (AIDS) have been reported in countries
throughout the world. Initial surveillance studies in Central Africa suggest an annual …

The origin and antiquity of syphilis: paleopathological diagnosis and interpretation [and comments and reply]

BJ Baker, GJ Armelagos, MJ Becker… - Current …, 1988 - journals.uchicago.edu
A review of the literature regarding the origin of syphilis in the light of paleopathological
diagnosis and interpretation strongly suggests a New World origin. Whereas the evidence …

Human immunodeficiency virus type 2 infection associated with AIDS in West Africa

F Clavel, K Mansinho, S Chamaret… - … England Journal of …, 1987 - Mass Medical Soc
We recently reported the isolation of a new retrovirus, termed human immunodeficiency
virus type 2 (HIV-2), from two West African patients with the acquired immunodeficiency …

Genetic variability of the AIDS virus: nucleotide sequence analysis of two isolates from African patients

M Alizon, S Wain-Hobson, L Montagnier, P Sonigo - Cell, 1986 - cell.com
To define further the genetic variability of the human AIDS retrovirus, we have cloned and
sequenced the complete genomes of two isolates obtained from Zairian patients Their …