Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

The future of ancient DNA: technical advances and conceptual shifts

M Hofreiter, JLA Paijmans, H Goodchild… - …, 2015 - Wiley Online Library
Technological innovations such as next generation sequencing and DNA hybridisation
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …

[HTML][HTML] Reconstructing prehistoric African population structure

P Skoglund, JC Thompson, ME Prendergast, A Mittnik… - Cell, 2017 - cell.com
We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently
divergent lineage that comprises the primary ancestry of the southern African San had a …

[HTML][HTML] Complete genomes reveal signatures of demographic and genetic declines in the woolly mammoth

E Palkopoulou, S Mallick, P Skoglund, J Enk… - Current Biology, 2015 - cell.com
The processes leading up to species extinctions are typically characterized by prolonged
declines in population size and geographic distribution, followed by a phase in which …

Reconstructing ancient genomes and epigenomes

L Orlando, MTP Gilbert, E Willerslev - Nature Reviews Genetics, 2015 - nature.com
Research involving ancient DNA (aDNA) has experienced a true technological revolution in
recent years through advances in the recovery of aDNA and, particularly, through …

LEA 3: Factor models in population genetics and ecological genomics with R

C Gain, O François - Molecular Ecology Resources, 2021 - Wiley Online Library
A major objective of evolutionary biology is to understand the processes by which organisms
have adapted to various environments, and to predict the response of organisms to new or …

Spatial population genetics: It's about time

GS Bradburd, PL Ralph - Annual review of ecology, evolution …, 2019 - annualreviews.org
Many important questions about the history and dynamics of organisms have a geographical
component: How many are there, and where do they live? How do they move and interbreed …

Spatiotemporal landscape genetics: Investigating ecology and evolution through space and time

LE Fenderson, AI Kovach, B Llamas - Molecular Ecology, 2020 - Wiley Online Library
Genetic time‐series data from historical samples greatly facilitate inference of past
population dynamics and species evolution. Yet, although climate and landscape change …

Intermediate degrees of synergistic pleiotropy drive adaptive evolution in ecological time

L Frachon, C Libourel, R Villoutreix, S Carrère… - Nature ecology & …, 2017 - nature.com
Rapid phenotypic evolution of quantitative traits can occur within years, but its underlying
genetic architecture remains uncharacterized. Here we test the theoretical prediction that …

Inference of natural selection from ancient DNA

M Dehasque, MC Ávila-Arcos… - Evolution …, 2020 - academic.oup.com
Evolutionary processes, including selection, can be indirectly inferred based on patterns of
genomic variation among contemporary populations or species. However, this often requires …