Novel hybrid molecules based on triazole-β-lactam as potential biological agents

P Shiri - Mini Reviews in Medicinal Chemistry, 2021 - ingentaconnect.com
Triazole ring is a cyclic scaffold containing three heteroatoms of nitrogen. They display a
broad variety of biological activities. The uncatalyzed/catalyzed 1, 3-dipolar cycloadditions …

Recent developments on 1, 8-Naphthalimide moiety as potential target for anticancer agents

R Tandon, V Luxami, N Tandon, K Paul - Bioorganic Chemistry, 2022 - Elsevier
Naphthalimide moiety is well known to possess various biological activities as it can very
well intercalate with DNA. In recent years, much of the attention has been given to the …

Potent antiproliferative active agents: novel bis Schiff bases and bis spiro β-lactams bearing isatin tethered with butylene and phenylene as spacer and DNA/BSA …

M Bashiri, A Jarrahpour, SM Nabavizadeh… - Medicinal Chemistry …, 2021 - Springer
Abstract A [2+ 2]-cycloaddition of bis-isatin Schiff bases 5a–b and 7 with activated
aryloxyacetic acid derivatives 8a–d afforded bis-spiroisatino β-lactams with aliphatic and …

Sulfonamide‐β‐lactam Hybrids Incorporating the Piperazine Moiety as Potential Antiinflammatory Agent with Promising Antibacterial Activity

R Heiran, A Jarrahpour, E Riazimontazer… - …, 2021 - Wiley Online Library
Several monocyclic β‐lactams have been synthesized via a [2+ 2] ketene–imine
cycloaddition reaction (Staudinger reaction) and evaluated for their biological activities. The …

Design, synthesis, biological evaluation and multi spectroscopic studies of novel 2-styrylquinoline-carboxamide derivatives as potential DNA intercalating anticancer …

N Omidkhah, A Gheisari, SR Oskuei, J Chamani… - Bioorganic …, 2024 - Elsevier
In this study, novel 2-styrylquinoline derivatives possessing a planar aromatic system and a
flexible side chain with an amino substituent were designed and synthesized as DNA …

[HTML][HTML] An Overview of Naphthylimide as Specific Scaffold for New Drug Discovery

W Ruan, Z Xie, Y Wang, L Xia, Y Guo, D Qiao - Molecules, 2024 - mdpi.com
Naphthylimides play a pivotal role as aromatic heterocyclic compounds, serving as the
foundational structures for numerous pharmacologically significant drugs. These drugs …

Recent advances in β-lactam derivatives as potential anticancer agents

X Zhang, Y Jia - Current Topics in Medicinal Chemistry, 2020 - ingentaconnect.com
Cancer, accounts for around 10 million deaths annually, is the second leading cause of
death globally. The continuous emergency of drug-resistant cancers and the low specificity …

Spectroscopic studies on the interaction of naphthyridines with DNA and fluorescent detection of DNA in agarose gel

G Mahalakshmi, B Selvakumar, KN Vennila… - Journal of …, 2021 - Springer
Four new naphthyridine derivatives (R1-R4) possessing amino acid or boronic acid moieties
have been synthesized and characterized using 1 H and 13 C NMR, FT-IR, and mass …

Four-membered ring systems

J Anaya, RM Sánchez - Progress in Heterocyclic Chemistry, 2021 - Elsevier
This chapter covers work published in the calendar year 2020. The synthesis and reactivity
of four-membered heteroatom-containing cycles are reviewed. New developments in the …

Sinteza funkcionalnih derivata 1, 8-naftalimida

A Čeke Trišler - 2024 - repozitorij.kemija.unios.hr
Sažetak U okviru ovoga završnog rada opisan je pokušaj priprave naftalimidnog derivata,
spoja (2) s ciljem njegove primjene u detekciji sumporovodika (H2S). Za pripravu ciljnog …