Formation and function of bacterial organelles
C Greening, T Lithgow - Nature Reviews Microbiology, 2020 - nature.com
Advances in imaging technologies have revealed that many bacteria possess organelles
with a proteomically defined lumen and a macromolecular boundary. Some are bound by a …
with a proteomically defined lumen and a macromolecular boundary. Some are bound by a …
Encapsulins
TW Giessen - Annual review of biochemistry, 2022 - annualreviews.org
Subcellular compartmentalization is a defining feature of all cells. In prokaryotes,
compartmentalization is generally achieved via protein-based strategies. The two main …
compartmentalization is generally achieved via protein-based strategies. The two main …
[HTML][HTML] Genetically encoded multimeric tags for subcellular protein localization in cryo-EM
Cryo-electron tomography (cryo-ET) allows for label-free high-resolution imaging of
macromolecular assemblies in their native cellular context. However, the localization of …
macromolecular assemblies in their native cellular context. However, the localization of …
A widespread bacterial protein compartment sequesters and stores elemental sulfur
R Benisch, MP Andreas, TW Giessen - Science Advances, 2024 - science.org
Subcellular compartments often serve to store nutrients or sequester labile or toxic
compounds. As bacteria mostly do not possess membrane-bound organelles, they often …
compounds. As bacteria mostly do not possess membrane-bound organelles, they often …
[HTML][HTML] Structural basis for peroxidase encapsulation inside the encapsulin from the Gram-negative pathogen Klebsiella pneumoniae
JA Jones, MP Andreas, TW Giessen - Nature Communications, 2024 - nature.com
Encapsulins are self-assembling protein nanocompartments capable of selectively
encapsulating dedicated cargo proteins, including enzymes involved in iron storage, sulfur …
encapsulating dedicated cargo proteins, including enzymes involved in iron storage, sulfur …
Advances in encapsulin nanocompartment biology and engineering
JA Jones, TW Giessen - Biotechnology and bioengineering, 2021 - Wiley Online Library
Compartmentalization is an essential feature of all cells. It allows cells to segregate and
coordinate physiological functions in a controlled and ordered manner. Different …
coordinate physiological functions in a controlled and ordered manner. Different …
Encapsulin cargo loading: progress and potential
JA Jones, R Benisch, TW Giessen - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Encapsulins are a recently discovered class of prokaryotic self-assembling icosahedral
protein nanocompartments measuring between 24 and 42 nm in diameter, capable of …
protein nanocompartments measuring between 24 and 42 nm in diameter, capable of …
[HTML][HTML] Large-scale computational discovery and analysis of virus-derived microbial nanocompartments
MP Andreas, TW Giessen - Nature Communications, 2021 - nature.com
Encapsulins are a class of microbial protein compartments defined by the viral HK97-fold of
their capsid protein, self-assembly into icosahedral shells, and dedicated cargo loading …
their capsid protein, self-assembly into icosahedral shells, and dedicated cargo loading …
Cryo-EM structure of Mycobacterium smegmatis DyP-loaded encapsulin
Y Tang, A Mu, Y Zhang, S Zhou… - Proceedings of the …, 2021 - National Acad Sciences
Encapsulins containing dye-decolorizing peroxidase (DyP)-type peroxidases are ubiquitous
among prokaryotes, protecting cells against oxidative stress. However, little is known about …
among prokaryotes, protecting cells against oxidative stress. However, little is known about …
Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism
E Eren, B Wang, DC Winkler, NR Watts, AC Steven… - Structure, 2022 - cell.com
Encapsulins are bacterial organelle-like cages involved in various aspects of metabolism,
especially protection from oxidative stress. They can serve as vehicles for a wide range of …
especially protection from oxidative stress. They can serve as vehicles for a wide range of …