[HTML][HTML] The model of local axon homeostasis-explaining the role and regulation of microtubule bundles in axon maintenance and pathology
Axons are the slender, cable-like, up to meter-long projections of neurons that electrically
wire our brains and bodies. In spite of their challenging morphology, they usually need to be …
wire our brains and bodies. In spite of their challenging morphology, they usually need to be …
[HTML][HTML] A conceptual view at microtubule plus end dynamics in neuronal axons
Axons are the cable-like protrusions of neurons which wire up the nervous system. Polar
bundles of microtubules (MTs) constitute their structural backbones and are highways for life …
bundles of microtubules (MTs) constitute their structural backbones and are highways for life …
[HTML][HTML] Drosophila Short stop as a paradigm for the role and regulation of spectraplakins
Spectraplakins are evolutionarily well conserved cytoskeletal linker molecules that are true
members of three protein families: plakins, spectrins and Gas2-like proteins. Spectraplakin …
members of three protein families: plakins, spectrins and Gas2-like proteins. Spectraplakin …
[HTML][HTML] The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis
PB Jain, PS Guerreiro, S Canato, F Janody - Scientific Reports, 2019 - nature.com
Aberrant expression of the Spectraplakin Dystonin (DST) has been observed in various
cancers, including those of the breast. However, little is known about its role in …
cancers, including those of the breast. However, little is known about its role in …
[图书][B] First in Fly: Drosophila Research and Biological Discovery
SE Mohr - 2018 - books.google.com
A single species of fly, Drosophila melanogaster, has been the subject of scientific research
for more than one hundred years. Why does this tiny insect merit such intense scrutiny …
for more than one hundred years. Why does this tiny insect merit such intense scrutiny …
[HTML][HTML] Coordinated crosstalk between microtubules and actin by a spectraplakin regulates lumen formation and branching
D Ricolo, SJ Araujo - Elife, 2020 - elifesciences.org
Subcellular lumen formation by single-cells involves complex cytoskeletal remodelling. We
have previously shown that centrosomes are key players in the initiation of subcellular …
have previously shown that centrosomes are key players in the initiation of subcellular …
The spectraplakin Short stop is an essential microtubule regulator involved in epithelial closure in Drosophila
Dorsal closure of the Drosophila embryonic epithelium provides an excellent model system
for the in vivo analysis of molecular mechanisms regulating cytoskeletal rearrangements. In …
for the in vivo analysis of molecular mechanisms regulating cytoskeletal rearrangements. In …
The Drosophila spectraplakin Short stop regulates focal adhesion dynamics by cross-linking microtubules and actin
AJ Zhao, J Montes-Laing, WMG Perry… - Molecular Biology of …, 2022 - Am Soc Cell Biol
The spectraplakin family of proteins includes ACF7/MACF1 and BPAG1/dystonin in
mammals, VAB-10 in Caenorhabditis elegans, Magellan in zebrafish, and Short stop (Shot) …
mammals, VAB-10 in Caenorhabditis elegans, Magellan in zebrafish, and Short stop (Shot) …
[HTML][HTML] Drosophila Primary Neuronal Cultures as a Useful Cellular Model to Study and Image Axonal Transport
A Voelzmann, N Sanchez-Soriano - Axonal Transport: Methods and …, 2022 - Springer
The use of primary neuronal cultures generated from Drosophila tissue provides a powerful
model for studies of transport mechanisms. Cultured fly neurons provide similarly detailed …
model for studies of transport mechanisms. Cultured fly neurons provide similarly detailed …
Re‐evaluating the actin‐dependence of spectraplakin functions during axon growth and maintenance
Axons are the long and slender processes of neurons constituting the biological cables that
wire the nervous system. The growth and maintenance of axons require loose microtubule …
wire the nervous system. The growth and maintenance of axons require loose microtubule …