Extracellular matrices (ECM s) are highly specialized and dynamic three‐dimensional (3D)
scaffolds into which cells reside in tissues. ECM is composed of a variety of fibrillar …

Basement membranes are delicate, nanoscale and pliable sheets of extracellular matrices
that often act as linings or partitions in organisms. Previously considered as passive …

The extracellular matrix (ECM) is a highly dynamic and heterogeneous structure that plays
multiple roles in living organisms. Its integrity and homeostasis are crucial for normal tissue …

Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all
vertebrate classes. In mammals, bile salt composition is determined by host and microbial …

In eukaryotes, precise pre-mRNA processing, including alternative splicing, is essential to
carry out the intricate protein translation process. Both point mutations (that alter the …

Biologics, like peptides, proteins and nucleic acids, have proven to be promising drugs for
the treatment of numerous diseases. However, besides the off label use of the monoclonal …

Visual impairment and blindness are common and seriously affect people's work and quality
of life in the world. Therefore, the effective therapies for eye diseases are of high priority …

Corneal blindness is the fifth leading cause of blindness worldwide, and therapeutic options
are still often limited to corneal transplantation. The corneal epithelium has a strong barrier …

Despite the obvious morphological differences in the visual system, zebrafish share a similar
architecture and components of the same embryonic origin as humans. The zebrafish retina …

This study aimed to develop a corneal epithelial injury model in zebrafish (Danio rerio) and
investigate the effectiveness of polydeoxyribonucleotide (PDRN) treatment on in vivo …