Superoxide dismutases (SODs) constitute a very important antioxidant defense against
oxidative stress in the body. The enzyme acts as a good therapeutic agent against reactive …

Reperfusion injury, the paradoxical tissue response that is manifested by blood flow-
deprived and oxygen-starved organs following the restoration of blood flow and tissue …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Oxidative stress plays a pivotal role in the development of diabetes complications, both
microvascular and cardiovascular. The metabolic abnormalities of diabetes cause …

Diabetic retinopathy is one of the most serious microvascular complications induced by
hyperglycemia via five major pathways, including polyol, hexosamine, protein kinase C, and …

Enzyme mimics or artificial enzymes are a class of catalysts that have been actively pursued
for decades and have heralded much interest as potentially viable alternatives to natural …

This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Introduction: Diabetic retinopathy (DR) is the leading cause of vision loss in the working age
population of the developed world. DR encompasses a complex pathology, and one that is …

Diabetes-specific microvascular disease is a leading cause of blindness, renal failure and
nerve damage, and diabetes-accelerated atherosclerosis leads to increased risk of …

At high concentrations, free radicals and radical-derived, nonradical reactive species are
hazardous for living organisms and damage all major cellular constituents. At moderate …