Cellular uptake of nanoparticles versus small molecules: a matter of size
J Mosquera, I García… - Accounts of chemical …, 2018 - ACS Publications
Conspectus The primary function of the cell membrane is to protect cells from their
surroundings. This entails a strict regulation on controlling the exchange of matter between …
surroundings. This entails a strict regulation on controlling the exchange of matter between …
Combination of cell-penetrating peptides with nanoparticles for therapeutic application: a review
Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane
translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid …
translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid …
Therapeutic targeting of non-coding RNAs in cancer
O Slaby, R Laga, O Sedlacek - Biochemical journal, 2017 - portlandpress.com
The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …
Production and clinical development of nanoparticles for gene delivery
Gene therapy is a promising strategy for specific treatment of numerous gene-associated
human diseases by intentionally altering the gene expression in pathological cells. A …
human diseases by intentionally altering the gene expression in pathological cells. A …
Poly (lactic acid) nanoparticles and cell-penetrating peptide potentiate mRNA-based vaccine expression in dendritic cells triggering their activation
AL Coolen, C Lacroix, P Mercier-Gouy, E Delaune… - Biomaterials, 2019 - Elsevier
Messenger RNA-based vaccines have the potential to trigger robust cytotoxic immune
responses, which are essential for fighting cancer and infectious diseases like HIV. Dendritic …
responses, which are essential for fighting cancer and infectious diseases like HIV. Dendritic …
Cell-penetrating peptides: strategies for anticancer treatment
D Raucher, JS Ryu - Trends in molecular medicine, 2015 - cell.com
Cell-penetrating peptides (CPP) provide an efficient strategy for the intracellular delivery of
bioactive molecules in various biomedical applications. This review focuses on recent …
bioactive molecules in various biomedical applications. This review focuses on recent …
Designing improved active peptides for therapeutic approaches against infectious diseases
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
[HTML][HTML] Cell penetrating peptides in preclinical and clinical cancer diagnosis and therapy
Delivery of imaging reagents and drugs to tumors is essential for cancer diagnosis and
therapy. In addition to therapeutic and diagnostic functionalities, peptides have potential …
therapy. In addition to therapeutic and diagnostic functionalities, peptides have potential …
Enzyme-triggered transcytosis of drug carrier system for deep penetration into hepatoma tumors
H Yan, P Xu, H Ma, Y Li, R Zhang, H Cong, B Yu… - Biomaterials, 2023 - Elsevier
In recent years, nano-drug delivery systems have made considerable progress in the
direction of tumor treatment, but the low permeability of drugs has restricted the development …
direction of tumor treatment, but the low permeability of drugs has restricted the development …
Peptide-based nanoassemblies in gene therapy and diagnosis: paving the way for clinical application
Nanotechnology approaches play an important role in developing novel and efficient
carriers for biomedical applications. Peptides are particularly appealing to generate such …
carriers for biomedical applications. Peptides are particularly appealing to generate such …