Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Preeclampsia evolves in 2 stages: a placental problem that generates signals to the mother
to cause a range of responses that comprise the second stage (preeclampsia syndrome) …

Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …

Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are
now known to mediate physiological and pathological functions throughout the body. We …

Preeclampsia (PE) is a complex disorder that is characterized by hypertension and
proteinuria after the 20th week of pregnancy, and it causes most neonatal morbidity and …

Mitochondria are indispensable organelles for maintaining cell energy metabolism, and also
are necessary to retain cell biological function by transmitting information as signal …

Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …

Human pregnancy depends on the proper development of the embryo prior to implantation
and the implantation of the embryo into the uterine wall. During the pre-implantation phase …

Preeclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality
worldwide. Defects in trophoblast invasion, differentiation of extravillous trophoblasts and …