Combating mosquito-borne diseases using genetic control technologies
Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …
burdens. Unfortunately, current control methods based on insecticides and environmental …
Wolbachia as translational science: controlling mosquito-borne pathogens
EP Caragata, HLC Dutra, PHF Sucupira… - Trends in …, 2021 - cell.com
In this review we examine how exploiting the Wolbachia–mosquito relationship has become
an increasingly popular strategy for controlling arbovirus transmission. Field deployments of …
an increasingly popular strategy for controlling arbovirus transmission. Field deployments of …
Human antibodies for viral infections
JE Crowe Jr - Annual review of immunology, 2022 - annualreviews.org
Antibodies have been used to prevent or treat viral infections since the nineteenth century,
but the full potential to use passive immunization for infectious diseases has yet to be …
but the full potential to use passive immunization for infectious diseases has yet to be …
Mimicking superinfection exclusion disrupts alphavirus infection and transmission in the yellow fever mosquito Aedes aegypti
CM Reitmayer, E Levitt, S Basu… - Proceedings of the …, 2023 - National Acad Sciences
Multiple viruses, including pathogenic viruses, bacteriophages, and even plant viruses,
cause a phenomenon termed superinfection exclusion whereby a currently infected cell is …
cause a phenomenon termed superinfection exclusion whereby a currently infected cell is …
Inherently confinable split-drive systems in Drosophila
CRISPR-based gene-drive systems, which copy themselves via gene conversion mediated
by the homology-directed repair (HDR) pathway, have the potential to revolutionize vector …
by the homology-directed repair (HDR) pathway, have the potential to revolutionize vector …
Manipulating the destiny of wild populations using CRISPR
Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
A Review: Wolbachia-Based Population Replacement for Mosquito Control Shares Common Points with Genetically Modified Control Approaches
PS Yen, AB Failloux - Pathogens, 2020 - mdpi.com
The growing expansion of mosquito vectors has made mosquito-borne arboviral diseases a
global threat to public health, and the lack of licensed vaccines and treatments highlight the …
global threat to public health, and the lack of licensed vaccines and treatments highlight the …
Advances and challenges in synthetic biology for mosquito control
Mosquito-borne illnesses represent a significant global health peril, resulting in
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
Dengue virus neutralizing antibody: a review of targets, cross-reactivity, and antibody-dependent enhancement
Dengue is the most common viral infection spread by mosquitoes, prevalent in tropical
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …
Assessment of a split homing based gene drive for efficient knockout of multiple genes
Homing based gene drives (HGD) possess the potential to spread linked cargo genes into
natural populations and are poised to revolutionize population control of animals. Given that …
natural populations and are poised to revolutionize population control of animals. Given that …