Sarcopenia is an age-associated decline of skeletal muscle mass and function and is known
to lead to frailty, cachexia, osteoporosis, metabolic syndromes, and death. Notwithstanding …

Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines
in skeletal muscle mitochondria are thought to play a primary role in this process …

Muscle loss during aging and disuse is a highly prevalent and disabling condition, but
knowledge about cellular pathways mediating muscle atrophy is still limited. Given the …

Inactivity is a recognized compounding factor in sarcopenia and muscle weakness in old
age. However, while the negative effects of unloading on skeletal muscle in young …

Memory is a process in which information is encoded, stored, and retrieved. For vertebrates,
the modern view has been that it occurs only in the brain. This review describes a cellular …

Age-related loss of muscle mass and strength can be accelerated by impaired recovery of
muscle mass following a transient atrophic stimulus. The aim of this study was to identify the …

During aging, skeletal muscle undergoes sarcopenia, a condition characterized by a loss of
muscle cell mass and alterations in contractile function. The origin of these decrements is …

Oxidative stress has been implicated in the etiology of age-related muscle loss (sarcopenia).
However, the underlying mechanisms by which oxidative stress contributes to sarcopenia …

Muscle fibres have different properties with respect to force, contraction speed, endurance,
oxidative/glycolytic capacity etc. Although adult muscle fibres are normally post‐mitotic with …

Maintenance of skeletal muscle is essential for health and survival. There are marked losses
of skeletal muscle mass as well as strength and physiological function under conditions of …