Over the past two decades, research has heavily emphasized basic mechanisms that
irreversibly damage brain cells after stroke. Much attention has focused on what makes …

One early phase of atherosclerosis involves the recruitment of inflammatory cells from the
circulation and their transendothelial migration. This process is predominantly mediated by …

Acute ischemic stroke is treatable, and our ability to treat patients with ischemic stroke
continues to improve. Since the publication of the first edition of this book, important changes …

Background—Evidence suggests that C-reactive protein (CRP) is related to thromboembolic
(TE) stroke. Whether associations are altered in the presence of other risk factors is unclear …

Background and Purpose—Substantial evidence is accumulating suggesting that
hyperhomocysteinemia may be a risk factor for ischemic stroke. Results of prospective …

OBJECTIVE. Stroke is the third leading cause of death and the leading cause of severe
disability. During the??? decade of the brain??? in the 1990s, the most promising …

Background and Purpose—Emerging technologies have made it possible to simultaneously
evaluate a large number of circulating proteins as potential new stroke risk markers …

Background and Purpose—Interleukin-6 (IL-6) and intercellular adhesion molecule-1 (ICAM-
1) are involved in the pathogenetic mechanisms responsible for several ischemic …

Objective In patients with type 2 diabetes mellitus (T2DM), biomarkers reflecting
inflammation and endothelial dysfunction have been linked to cardiovascular disease (CVD …

Modern medicine is facing an increasing number of treatments available for vascular and
neurodegenerative brain diseases, but no causal or neuroprotective treatment has yet been …