[HTML][HTML] Acute encephalitis–diagnosis and management

M Ellul, T Solomon - Clinical medicine, 2018 - Elsevier
Encephalitis, inflammation of the brain, is most commonly caused by a viral infection
(especially herpes simplex virus [HSV] type 1 in the UK) although autoimmune causes, such …

[HTML][HTML] Encephalitis diagnosis using metagenomics: application of next generation sequencing for undiagnosed cases

JR Brown, T Bharucha, J Breuer - Journal of infection, 2018 - Elsevier
Background Current estimates suggest that even in the most resourced settings, the
aetiology of encephalitis is identified in less than half of clinical cases. It is acknowledged …

Herpes simplex virus encephalitis update

JP Stahl, A Mailles - Current Opinion in Infectious Diseases, 2019 - journals.lww.com
Herpes simplex virus encephalitis update : Current Opinion in Infectious Diseases Herpes
simplex virus encephalitis update : Current Opinion in Infectious Diseases Log in or Register …

Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter …

R Sonneville, E de Montmollin, D Contou, R Ferrer… - Intensive care …, 2023 - Springer
Purpose We aimed to characterize the outcomes of patients with severe
meningoencephalitis requiring intensive care. Methods We conducted a prospective …

Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection

Y Zhang, P Cui, HC Zhang, HL Wu, MZ Ye… - Journal of translational …, 2020 - Springer
Background Accurate etiology diagnosis is crucial for central nervous system infections
(CNS infections). The diagnostic value of metagenomic next-generation sequencing …

State of the art: acute encephalitis

KC Bloch, C Glaser, D Gaston… - Clinical Infectious …, 2023 - academic.oup.com
Encephalitis is a devastating neurologic disease often complicated by prolonged neurologic
deficits. Best practices for the management of adult patients include universal testing for a …

Assessment of magnetic resonance imaging changes and functional outcomes among adults with severe herpes simplex encephalitis

B Sarton, P Jaquet, D Belkacemi… - JAMA Network …, 2021 - jamanetwork.com
Importance Current guidelines recommend brain magnetic resonance imaging (MRI) for
clinical management of patients with severe herpes simplex encephalitis (HSE). However …

Changing profile of encephalitis: results of a 4-year study in France

A Mailles, X Argemi, C Biron, P Fillatre… - Infectious diseases …, 2022 - Elsevier
Context In 2007, we performed a nationwide prospective study to assess the epidemiology
of encephalitis in France. We aimed to evaluate epidemiological changes 10 years later …

[HTML][HTML] Diagnostic challenges of central nervous system infection: extensive multiplex panels versus stepwise guided approach

P Vetter, M Schibler, JL Herrmann… - Clinical Microbiology and …, 2020 - Elsevier
Background Cerebrospinal fluid (CSF) testing is a key component for the diagnosis of
central nervous system (CNS) infections. Current meningitis and encephalitis management …

Combining metagenomic sequencing with whole exome sequencing to optimize clinical strategies in neonates with a suspected central nervous system infection

M Ge, M Gan, K Yan, F Xiao, L Yang, B Wu… - Frontiers in cellular …, 2021 - frontiersin.org
Objectives Central nervous system (CNS) infection has a high incidence and mortality in
neonates, but conventional tests are time-consuming and have a low sensitivity. Some rare …