[HTML][HTML] Non-B DNA structures as a booster of genome instability
RC Duardo, F Guerra, S Pepe, G Capranico - Biochimie, 2023 - Elsevier
Non-canonical secondary structures (NCSs) are alternative nucleic acid structures that differ
from the canonical B-DNA conformation. NCSs often occur in repetitive DNA sequences and …
from the canonical B-DNA conformation. NCSs often occur in repetitive DNA sequences and …
CH groups as donors in hydrogen bonds: a historical overview and occurrence in proteins and nucleic acids
ZS Derewenda - International Journal of Molecular Sciences, 2023 - mdpi.com
Hydrogen bonds constitute a unique type of non-covalent interaction, with a critical role in
biology. Until fairly recently, the canonical view held that these bonds occur between …
biology. Until fairly recently, the canonical view held that these bonds occur between …
DNA-Interactive and Damage Study with meso-Tetra(2-thienyl)porphyrins Coordinated with Polypyridyl Pd(II) and Pt(II) Complexes
BA Iglesias, NP Peranzoni, SI Faria, LB Trentin… - Molecules, 2023 - mdpi.com
We report the DNA-binding properties of three porphyrins with peripheral thienyl
substituents (TThPor, PdTThPor and PtTThPor). The binding capacity of each porphyrin with …
substituents (TThPor, PdTThPor and PtTThPor). The binding capacity of each porphyrin with …
NBBC: a non-B DNA burden explorer in cancer
Q Xu, J Kowalski - Nucleic Acids Research, 2023 - academic.oup.com
Abstract Alternate (non-B) DNA-forming structures, such as Z-DNA, G-quadruplex, triplex
have demonstrated a potential role in cancer etiology. It has been found that non-B DNA …
have demonstrated a potential role in cancer etiology. It has been found that non-B DNA …
DNA‐Targeted Complexes of Tc and Re for Biomedical Applications
E Palma, JF Santos, C Fernandes… - Chemistry–A European …, 2024 - Wiley Online Library
Due to their favorable chemical features, Re and Tc complexes have been widely used for
the development of new therapeutic agents and imaging probes to solve problems of …
the development of new therapeutic agents and imaging probes to solve problems of …
Computational modeling of DNA 3D structures: From dynamics and mechanics to folding
DNA carries the genetic information required for the synthesis of RNA and proteins and
plays an important role in many processes of biological development. Understanding the …
plays an important role in many processes of biological development. Understanding the …
Predicting the Three-Dimensional Structure of the c-KIT Proto-Oncogene Promoter and the Dynamics of Its Strongly Coupled Guanine Quadruplexes
Guanine quadruplexes (G4s) play essential protective and regulatory roles within cells,
influencing gene expression. In several gene-promoter regions, multiple G4-forming …
influencing gene expression. In several gene-promoter regions, multiple G4-forming …
Hyper Rayleigh scattering from DNA nucleotides in aqueous solution
C Jonin, M Dereniowski, E Salmon… - The Journal of …, 2023 - pubs.aip.org
Nucleotides are organic compounds consisting of a phosphate group, a nitrogenous base,
namely adenine (A), thymine (T), cytosine (C), or guanine (G), and a sugar, here …
namely adenine (A), thymine (T), cytosine (C), or guanine (G), and a sugar, here …
Structural basis of water-mediated cis Watson–Crick/Hoogsteen base-pair formation in non-CpG methylation
SM Lin, HT Huang, PJ Fang, CF Chang… - Nucleic Acids …, 2024 - academic.oup.com
Non-CpG methylation is associated with several cellular processes, especially neuronal
development and cancer, while its effect on DNA structure remains unclear. We have …
development and cancer, while its effect on DNA structure remains unclear. We have …
Computational Design of Photosensitive Polymer Templates To Drive Molecular Nanofabrication
Molecular electronics promises the ultimate level of miniaturization of computers and other
machines as organic molecules are the smallest known physical objects with nontrivial …
machines as organic molecules are the smallest known physical objects with nontrivial …