Molecular mechanisms of dietary restriction promoting health and longevity

CL Green, DW Lamming, L Fontana - Nature Reviews Molecular Cell …, 2022 - nature.com
Dietary restriction with adequate nutrition is the gold standard for delaying ageing and
extending healthspan and lifespan in diverse species, including rodents and non-human …

Clinical application of intermittent fasting for weight loss: progress and future directions

KA Varady, S Cienfuegos, M Ezpeleta… - Nature Reviews …, 2022 - nature.com
Intermittent fasting diets have become very popular in the past few years, as they can
produce clinically significant weight loss. These diets can be defined, in the simplest of …

2021 ACC expert consensus decision pathway on the management of ASCVD risk reduction in patients with persistent hypertriglyceridemia: a report of the American …

SS Virani, PB Morris, A Agarwala… - Journal of the American …, 2021 - jacc.org
The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

Time-restricted eating for the prevention and management of metabolic diseases

ENC Manoogian, LS Chow, PR Taub… - Endocrine …, 2022 - academic.oup.com
Time-restricted feeding (TRF, animal-based studies) and time-restricted eating (TRE,
humans) are an emerging behavioral intervention approach based on the understanding of …

Cardiometabolic benefits of intermittent fasting

KA Varady, S Cienfuegos, M Ezpeleta… - Annual review of …, 2021 - annualreviews.org
This review aims to summarize the effects of intermittent fasting on markers of
cardiometabolic health in humans. All forms of fasting reviewed here—alternate-day fasting …

[HTML][HTML] Ten-hour time-restricted eating reduces weight, blood pressure, and atherogenic lipids in patients with metabolic syndrome

MJ Wilkinson, ENC Manoogian, A Zadourian, H Lo… - Cell metabolism, 2020 - cell.com
In animal models, time-restricted feeding (TRF) can prevent and reverse aspects of
metabolic diseases. Time-restricted eating (TRE) in human pilot studies reduces the risks of …

Circadian clocks and insulin resistance

DJ Stenvers, FAJL Scheer, P Schrauwen… - Nature Reviews …, 2019 - nature.com
Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Flipping the metabolic switch: understanding and applying the health benefits of fasting

SD Anton, K Moehl, WT Donahoo, K Marosi, SA Lee… - …, 2018 - Wiley Online Library
Objective Intermittent fasting (IF) is a term used to describe a variety of eating patterns in
which no or few calories are consumed for time periods that can range from 12 hours to …

Time-restricted eating to prevent and manage chronic metabolic diseases

A Chaix, ENC Manoogian, GC Melkani… - Annual review of …, 2019 - annualreviews.org
Molecular clocks are present in almost every cell to anticipate daily recurring and
predictable changes, such as rhythmic nutrient availability, and to adapt cellular functions …

The influence of meal frequency and timing on health in humans: the role of fasting

A Paoli, G Tinsley, A Bianco, T Moro - Nutrients, 2019 - mdpi.com
The influence of meal frequency and timing on health and disease has been a topic of
interest for many years. While epidemiological evidence indicates an association between …