Bioorthogonal Reactions in Bioimaging

E Kozma, P Kele - Topics in Current Chemistry, 2024 - Springer
Visualization of biomolecules in their native environment or imaging-aided understanding of
more complex biomolecular processes are one of the focus areas of chemical biology …

Hyper-Responsive Chemiluminescent Probe Reveals Distinct PYRase Activity in Pseudomonas aeruginosa

R Tannous, O Shelef, T Kopp, M Fridman… - Bioconjugate …, 2024 - ACS Publications
Pyrrolidone carboxyl peptidase, commonly known as PYRase, is an exopeptidase that
catalytically cleaves an N-terminal pyroglutamic acid from peptides or proteins. The diverse …

Spiro-strain Takes Chemiluminescence to Flash-Mode

SK Das, A Datta - 2024 - ACS Publications
Spiro-strain Takes Chemiluminescence to Flash-Mode | ACS Central Science ACS ACS
Publications C&EN CAS Find my institution Log In ACS Central Science ACS Publications. Most …

Chemiexcitation Acceleration of 1, 2-Dioxetanes via a Spiro-Fused Inductive Electron-Withdrawing Motifs

M David, T Leirikh, O Shelef, S Gutkin, T Kopp, Q Zhou… - 2024 - chemrxiv.org
The chemiluminescent light-emission pathway of phenoxy-1, 2-dioxetane luminophores
attracts growing interest within the scientific community. Dioxetane probes undergoing rapid …

Boosting Chemiexcitation of Phenoxy-1, 2-Dioxetanes through 7-Norbornyl and Homocubanyl Spirofusion

S Gutkin, O Shelef, Z Babjaková, LA Tomanová… - 2024 - chemrxiv.org
The chemiluminescent light-emission pathway of phenoxy-1, 2-dioxetane luminophores is
increasingly attracting the scientific community's attention. Dioxetane probes that undergo …

Spiro-Substituted Dioxetane-Based Chemical Probes with Enhanced Detection and Sensitivity Limits

P Richardson - Synfacts, 2024 - thieme-connect.com
Significance: The design of chemical probes to track biological processes in cellular assays
is a critical research area with the speed of detection and sensitivity of such molecules is key …