Assessing the ecological risks of per‐and polyfluoroalkyl substances: Current state‐of‐the science and a proposed path forward

GT Ankley, P Cureton, RA Hoke… - Environmental …, 2021 - Wiley Online Library
Per‐and poly‐fluoroalkyl substances (PFAS) encompass a large, heterogenous group of
chemicals of potential concern to human health and the environment. Based on information …

Species sensitivity to toxic substances: Evolution, ecology and applications

D Spurgeon, E Lahive, A Robinson, S Short… - Frontiers in …, 2020 - frontiersin.org
Because it is only possible to test chemicals for effects on a restricted range of species and
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …

[HTML][HTML] Pharmaceuticals and personal care products (PPCPs) in surface water and fish from three Asian countries: Species-specific bioaccumulation and potential …

K Nozaki, R Tanoue, T Kunisue, NM Tue, S Fujii… - Science of The Total …, 2023 - Elsevier
In Asian developing countries, undeveloped and ineffective sewer systems are causing
surface water pollution by a lot of contaminants, especially pharmaceuticals and personal …

A broad‐taxa approach as an important concept in ecotoxicological studies and pollution monitoring

A Rosner, L Ballarin, S Barnay‐Verdier… - Biological …, 2024 - Wiley Online Library
Aquatic invertebrates play a pivotal role in (eco) toxicological assessments because they
offer ethical, cost‐effective and repeatable testing options. Additionally, their significance in …

An ancestral molecular response to nanomaterial particulates

G Del Giudice, A Serra, LA Saarimäki, K Kotsis… - Nature …, 2023 - nature.com
The varied transcriptomic response to nanoparticles has hampered the understanding of the
mechanism of action. Here, by performing a meta-analysis of a large collection of …

Toward an AOP network-based tiered testing strategy for the assessment of thyroid hormone disruption

D Knapen, E Stinckens, JE Cavallin… - Environmental …, 2020 - ACS Publications
A growing number of environmental pollutants are known to adversely affect the thyroid
hormone system, and major gaps have been identified in the tools available for the …

[HTML][HTML] Toxicity by descent: A comparative approach for chemical hazard assessment

JK Colbourne, JR Shaw, E Sostare, C Rivetti… - Environmental …, 2022 - Elsevier
Toxicology is traditionally divided between human and eco-toxicology. In the shared pursuit
of environmental health, this separation does not account for discoveries made in the …

The exposome and toxicology: a win–win collaboration

R Barouki, K Audouze, C Becker, L Blaha… - Toxicological …, 2022 - academic.oup.com
The development of the exposome concept has been one of the hallmarks of environmental
and health research for the last decade. The exposome encompasses the life course …

Towards precision ecotoxicology: Leveraging evolutionary conservation of pharmaceutical and personal care product targets to understand adverse outcomes across …

BW Brooks, S van den Berg, DA Dreier… - Environmental …, 2024 - Wiley Online Library
Translation of environmental science to the practice aims to protect biodiversity and
ecosystem services, and our future ability to do so relies on the development of a precision …

Reporting and reproducibility: Proteomics of fish models in environmental toxicology and ecotoxicology

AN Henke, S Chilukuri, LM Langan… - Science of The Total …, 2023 - Elsevier
Environmental toxicology and ecotoxicology research efforts are employing proteomics with
fish models as New Approach Methodologies, along with in silico, in vitro and other omics …