The vascular endothelium and coagulation: homeostasis, disease, and treatment, with a focus on the von willebrand factor and factors VIII and V

JAD Pablo-Moreno, LJ Serrano, L Revuelta… - International Journal of …, 2022 - mdpi.com
The vascular endothelium has several important functions, including hemostasis. The
homeostasis of hemostasis is based on a fine balance between procoagulant and …

The use of thromboelastography (TEG) and rotational thromboelastometry (ROTEM) in neonates: a systematic review

GΝ Katsaras, R Sokou, AG Tsantes, D Piovani… - European Journal of …, 2021 - Springer
Abstract “Developmental hemostasis” refers to the dynamic process of gradual hemostatic
maturation. Conventional coagulation tests seem to fail to accurately depict the in vivo …

Surface roughness of silk fibroin/alginate microspheres for rapid hemostasis in vitro and in vivo

X Huang, Q Fu, Y Deng, F Wang, B Xia, Z Chen… - Carbohydrate …, 2021 - Elsevier
Timely hemostatic treatment is important to reduce blood loss and improve survival. To
increase the speed of blood coagulation, hemostatic microspheres with varying degrees of …

Development and validation of a sepsis diagnostic scoring model for neonates with suspected sepsis

R Sokou, G Ioakeimidis, D Piovani… - Frontiers in …, 2022 - frontiersin.org
Background We aimed to develop and validate a diagnostic model for sepsis among
neonates evaluated for suspected sepsis, by incorporating thromboelastometry parameters …

Fresh frozen plasma transfusion in the neonatal population: a systematic review

R Sokou, S Parastatidou, A Konstantinidi, AG Tsantes… - Blood Reviews, 2022 - Elsevier
Although fresh frozen plasma (FFP) transfusions are common practice in neonatology,
robust evidence on their use is lacking. The aim of this study was to systematically review …

A risk score for predicting the incidence of hemorrhage in critically ill neonates: development and validation study

R Sokou, D Piovani, A Konstantinidi… - Thrombosis and …, 2021 - thieme-connect.com
The aim of the study was to develop and validate a prediction model for hemorrhage in
critically ill neonates which combines rotational thromboelastometry (ROTEM) parameters …

Update on the clot waveform analysis

H Wada, T Matsumoto, K Ohishi… - Clinical and Applied …, 2020 - journals.sagepub.com
The activated partial thromboplastin time (APTT)–clot waveform analysis (CWA) was
previously reported to be associated with the early detection of disseminated intravascular …

[HTML][HTML] Clot waveform analysis for hemostatic abnormalities

H Wada, K Shiraki, T Matsumoto… - Annals of …, 2023 - synapse.koreamed.org
Clot waveform analysis (CWA) observes changes in transparency in a plasma sample
based on clotting tests such as activated partial thromboplastin time (APTT), prothrombin …

The role of ROTEM variables based on clot elasticity and platelet component in predicting bleeding risk in thrombocytopenic critically ill neonates

S Parastatidou, R Sokou, AG Tsantes… - European Journal of …, 2021 - Wiley Online Library
Background Our aim was to investigate the role of thromboelastometry (ROTEM)
parameters, including maximum clot elasticity (MCE) and platelet component (PLTEM MCE …

Contemporary tools for evaluation of hemostasis in neonates. Where are we and where are we headed?

R Sokou, S Parastatidou, A Konstantinidi, AG Tsantes… - Blood Reviews, 2024 - Elsevier
The assessment of hemostatic disorders in neonates is crucial, but remains challenging for
clinicians. Although the concept of developmental hemostasis is widely accepted among …