Multimorbidity and functional impairment–bidirectional interplay, synergistic effects and common pathways

A Calderón‐Larrañaga, DL Vetrano… - Journal of internal …, 2019 - Wiley Online Library
This review discusses the interplay between multimorbidity (ie co‐occurrence of more than
one chronic health condition in an individual) and functional impairment (ie limitations in …

A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on …

MH Olsen, SY Angell, S Asma, P Boutouyrie, D Burger… - The Lancet, 2016 - thelancet.com
Executive summary Elevated blood pressure is the strongest modifiable risk factor for
cardiovascular disease worldwide. Despite extensive knowledge about ways to prevent as …

Kidney physiology and pathophysiology during heat stress and the modification by exercise, dehydration, heat acclimation and aging

CL Chapman, BD Johnson, MD Parker, D Hostler… - Temperature, 2021 - Taylor & Francis
The kidneys' integrative responses to heat stress aid thermoregulation, cardiovascular
control, and water and electrolyte regulation. Recent evidence suggests the kidneys are at …

Polypharmacy in the aging patient: management of hypertension in octogenarians

A Benetos, P Rossignol, A Cherubini, L Joly… - Jama, 2015 - jamanetwork.com
Importance Hypertension treatment is beneficial for most hypertensive patients. The benefits
for patients who are very old and frail, especially those taking numerous medications, are …

Prevalence and factors associated with polypharmacy: a systematic review and meta-analysis

M Delara, L Murray, B Jafari, A Bahji, Z Goodarzi… - BMC geriatrics, 2022 - Springer
Introduction Polypharmacy is commonly associated with adverse health outcomes. There
are currently no meta-analyses of the prevalence of polypharmacy or factors associated with …

Potentially inappropriate drug use among hospitalised older adults: results from the CRIME study

M Tosato, F Landi, AM Martone, A Cherubini… - Age and …, 2014 - academic.oup.com
Background: Beers criteria and screening tool of older person's prescriptions (STOPP)
criteria are widely used to assess potentially inappropriate drug use (PIDU). Objective: the …

Metabolic syndrome epidemic among Korean adults: Korean survey of Cardiometabolic Syndrome (2018)

JH Huh, DR Kang, JY Jang, JH Shin, JY Kim, S Choi… - Atherosclerosis, 2018 - Elsevier
Background and aims Little information exists on the prevalence of metabolic syndrome
(MetS) in Korea since 2007. We aimed to provide up-to-date estimates of the prevalence of …

Routine assessment of cognitive function in older patients with hypertension seen by primary care physicians: why and how—a decision-making support from the …

A Scuteri, A Benetos, C Sierra, A Coca… - Journal of …, 2021 - journals.lww.com
The guidelines on hypertension recently published by the European Societies of
Hypertension and Cardiology, have acknowledged cognitive function (and its decline) as a …

The role of European healthcare databases for post-marketing drug effectiveness, safety and value evaluation: where does Italy stand?

G Trifirò, R Gini, F Barone-Adesi, E Beghi, A Cantarutti… - Drug Safety, 2019 - Springer
Enormous progress has been made globally in the use of evidence derived from patients'
clinical information as they access their routine medical care. The value of real-world data …

Medication adherence in the older adults with chronic multimorbidity: a systematic review of qualitative studies on patient's experience

M Maffoni, S Traversoni, E Costa, L Midão… - European geriatric …, 2020 - Springer
Purpose Medication non-adherence represents a socially relevant challenge, particularly
when interlinked to multiple chronic diseases and polypharmacy. Non-adherence rates …