Neuroblastoma is a solid tumour that arises from the developing sympathetic nervous
system. Over the past decade, our understanding of this disease has advanced …

Bone and bone marrow are among the most frequent metastatic sites of cancer. The
occurrence of bone metastasis is frequently associated with a dismal disease outcome. The …

Metastatic cancer accounts for 90% of all cancer-related deaths and continues to be one of
the toughest challenges in cancer treatment. A growing body of data indicates that S100A9 …

Neuroblastoma is the most common extracranial pediatric tumor and often presents with
metastatic disease, and patients with high-risk neuroblastoma have survival rates of~ 50 …

Neuroblastoma (NB) is the most common extra-cranial solid tumor of childhood and arises
from developing sympathetic nervous system. Most primary tumors localize in the abdomen …

HLA-G is an HLA-class Ib molecule that is involved in the establishment of tolerance at the
maternal/fetal interface during pregnancy. The expression of HLA-G is highly restricted in …

Calprotectin (CP) is a calcium‐and zinc‐binding protein of the S100 family expressed mainly
by neutrophils with important extracellular activity. The aim of the current review is to …

Considering that the non-classical HLA-G molecule has well-recognized tolerogenic
properties, HLA-G expression is expected to be deleterious when present in tumor cells and …

According to the cancer immunoediting model, the interplay between tumor cells and the
host immune system is crucial for the control of tumor growth. NB is a pediatric tumor that …

HLA abnormalities on tumour cells for immune escape have been widely described. In
addition, cellular components of the tumour microenvironment, in particular myeloid derived …