The neural basis of reversal learning: An updated perspective
Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …
and have been used as assays, across species, for altered cognitive processes in a host of …
What the orbitofrontal cortex does not do
TA Stalnaker, NK Cooch, G Schoenbaum - Nature neuroscience, 2015 - nature.com
The number of papers about the orbitofrontal cortex (OFC) has grown from 1 per month in
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …
The role of the lateral orbitofrontal cortex in creating cognitive maps
We use mental models of the world—cognitive maps—to guide behavior. The lateral
orbitofrontal cortex (lOFC) is typically thought to support behavior by deploying these maps …
orbitofrontal cortex (lOFC) is typically thought to support behavior by deploying these maps …
Orbitofrontal cortex as a cognitive map of task space
Orbitofrontal cortex (OFC) has long been known to play an important role in decision
making. However, the exact nature of that role has remained elusive. Here, we propose a …
making. However, the exact nature of that role has remained elusive. Here, we propose a …
Neural basis of reinforcement learning and decision making
Reinforcement learning is an adaptive process in which an animal utilizes its previous
experience to improve the outcomes of future choices. Computational theories of …
experience to improve the outcomes of future choices. Computational theories of …
The mediodorsal thalamus: an essential partner of the prefrontal cortex for cognition
S Parnaudeau, SS Bolkan, C Kellendonk - Biological psychiatry, 2018 - Elsevier
Deficits in cognition are a core feature of many psychiatric conditions, including
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …
Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited
Obsessive-compulsive disorder (OCD) is a common, heritable and disabling
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …
[HTML][HTML] Inhibition of mediodorsal thalamus disrupts thalamofrontal connectivity and cognition
Cognitive deficits are central to schizophrenia, but the underlying mechanisms still remain
unclear. Imaging studies performed in patients point to decreased activity in the mediodorsal …
unclear. Imaging studies performed in patients point to decreased activity in the mediodorsal …
Evolving schema representations in orbitofrontal ensembles during learning
How do we learn about what to learn about? Specifically, how do the neural elements in our
brain generalize what has been learned in one situation to recognize the common structure …
brain generalize what has been learned in one situation to recognize the common structure …
[图书][B] The psychopath: Emotion and the brain.
J Blair, D Mitchell, K Blair - 2005 - psycnet.apa.org
Psychopathy is a disorder embedded in mystique, controversy and fantasy. Consistently
portrayed in the media and popular culture as unusual, inhumane and emotionless …
portrayed in the media and popular culture as unusual, inhumane and emotionless …