New developments in Cryptosporidium research

U Ryan, N Hijjawi - International journal for parasitology, 2015 - Elsevier
Cryptosporidium is an enteric parasite that is considered the second greatest cause of
diarrhoea and death in children after rotavirus. Currently, 27 species are recognised as valid …

It's official–Cryptosporidium is a gregarine: What are the implications for the water industry?

U Ryan, A Paparini, P Monis, N Hijjawi - Water Research, 2016 - Elsevier
Parasites of the genus Cryptosporidium are a major cause of diarrhoea and ill-health in
humans and animals and are frequent causes of waterborne outbreaks. Until recently, it was …

A stem-cell-derived platform enables complete Cryptosporidium development in vitro and genetic tractability

G Wilke, LJ Funkhouser-Jones, Y Wang, S Ravindran… - Cell host & …, 2019 - cell.com
Despite being a frequent cause of severe diarrheal disease in infants and an opportunistic
infection in immunocompromised patients, Cryptosporidium research has lagged due to a …

Life cycle progression and sexual development of the apicomplexan parasite Cryptosporidium parvum

J Tandel, ED English, A Sateriale, JA Gullicksrud… - Nature …, 2019 - nature.com
The apicomplexan parasite Cryptosporidium is a leading global cause of severe diarrhoeal
disease and an important contributor to early childhood mortality. Currently, there are no …

The Toxoplasma gondii Cyst Wall Protein CST1 Is Critical for Cyst Wall Integrity and Promotes Bradyzoite Persistence

T Tomita, DJ Bzik, YF Ma, BA Fox, LM Markillie… - PLoS …, 2013 - journals.plos.org
Toxoplasma gondii infects up to one third of the world's population. A key to the success of T.
gondii as a parasite is its ability to persist for the life of its host as bradyzoites within tissue …

Evolution of mitosome metabolism and invasion-related proteins in Cryptosporidium

S Liu, DM Roellig, Y Guo, N Li, MA Frace, K Tang… - BMC genomics, 2016 - Springer
Background The switch from photosynthetic or predatory to parasitic life strategies by
apicomplexans is accompanied with a reductive evolution of genomes and losses of …

The Cryptosporidium Parvum Transcriptome during In Vitro Development

MJ Mauzy, S Enomoto, CA Lancto, MS Abrahamsen… - PloS one, 2012 - journals.plos.org
Cryptosporidiosis is caused by an obligate intracellular parasite that has eluded global
transcriptional or proteomic analysis of the intracellular developmental stages. The transcript …

Cryptosporidium infections: molecular advances

M Lendner, A Daugschies - Parasitology, 2014 - cambridge.org
Cryptosporidium host cell interaction remains fairly obscure compared with other
apicomplexans such as Plasmodium or Toxoplasma. The reason for this is probably the …

Specific Cryptosporidium antigens associate with reinfection immunity and protection from cryptosporidiosis

CA Gilchrist, JJ Campo, JV Pablo… - The Journal of …, 2023 - Am Soc Clin Investig
There is no vaccine to protect from cryptosporidiosis, a leading cause of diarrhea in infants
in low-and middle-income countries. Here, we comprehensively identified parasite antigens …

Strategies to discover the structural components of cyst and oocyst walls

J Samuelson, GG Bushkin, A Chatterjee… - Eukaryotic …, 2013 - Am Soc Microbiol
Cysts of Giardia lamblia and Entamoeba histolytica and oocysts of Toxoplasma gondii and
Cryptosporidium parvum are the infectious and sometimes diagnostic forms of these …