Ondansetron: A Selective 5‐HT3 Receptor Antagonist and Its Applications in CNS‐Related Disorders

JH Ye, R Ponnudurai, R Schaefer - CNS drug reviews, 2001 - Wiley Online Library
Ondansetron is a selective 5‐hydroxytryptamine3 (5‐HT3) receptor antagonist that has been
introduced to clinical practice as an antiemetic for cancer treatment‐induced and anesthesia …

Ondansetron: therapeutic use as an antiemetic

RJ Milne, RC Heel - Drugs, 1991 - Springer
Summary Synopsis Ondansetron (GR 38032F) is a highly selective 5-HT 3 receptor
antagonist, one of a new class of compounds which may have several therapeutic …

[PDF][PDF] Recommendations for the use of antiemetics: evidence-based, clinical practice guidelines

RJ Gralla, D Osoba, MG Kris, P Kirkbride… - Journal of Clinical …, 1999 - Citeseer
THE GOAL OF ANTIEMETIC therapy is to prevent nausea and vomiting completely. This
goal is achieved for many patients receiving chemotherapy or radiation therapy, and is …

8 Gy single-dose radiotherapy is effective in metastatic spinal cord compression: results of a phase III randomized multicentre Italian trial

E Maranzano, F Trippa, M Casale, S Costantini… - Radiotherapy and …, 2009 - Elsevier
BACKGROUND AND PURPOSE: In a previous randomized trial we showed that the short-
course radiotherapy (RT) regimen of 8Gy× 2 was feasible in patients with metastatic spinal …

[图书][B] Medical management of radiation accidents

KS Cohen, I Gusev, A Guskova, FA Mettler - 2001 - taylorfrancis.com
Although radiation accidents are rare and often complex in nature, they are of great concern
not only to the patient and involved medical staff, but to the media and public as well. Yet …

Management of intractable nausea and vomiting in patients at the end of life:“I was feeling nauseous all of the time... nothing was working”

GJ Wood, JW Shega, B Lynch, JH Von Roenn - Jama, 2007 - jamanetwork.com
Nausea and vomiting, symptoms that occur commonly near the end of life, represent a
substantial source of physical and psychological distress for patients and families. In the …

Radiotherapy-induced nausea and vomiting (RINV): MASCC/ESMO guideline for antiemetics in radiotherapy: update 2009

PC Feyer, E Maranzano, A Molassiotis, F Roila… - Supportive Care in …, 2011 - Springer
Radiation-induced nausea and vomiting (RINV) are still often underestimated by radiation
oncologists. However, as many as 50–80% of patients undergoing radiotherapy (RT) will …

One third of patients with radiotherapy-induced nausea consider their antiemetic treatment insufficient

A Enblom, B Bergius Axelsson, G Steineck… - Supportive Care in …, 2009 - Springer
Objective To describe the prevalence of nausea and vomiting during radiotherapy and to
compare quality of life, psychological and functional status in patients experiencing or not …

Short-course radiotherapy (8 Gy× 2) in metastatic spinal cord compression: an effective and feasible treatment

E Maranzano, P Latini, E Perrucci, S Beneventi… - International Journal of …, 1997 - Elsevier
Purpose: To evalute the clinical outcome and toxicity of a short-course regiment of
radiotherapy (RT) in selected metastatic spinal cord compression (MSCC) patients. Methods …

[PDF][PDF] 5-HT3 Antagonists in Postoperative Nausea and Vomiting

D Russell, GNC Kenny - British Journal of Anaesthesia, 1992 - academia.edu
Postoperative nausea and vomIttng (PONV) are distressing side effects of anaesthesia and
surgery, with a high incidence after gynaecological surgery [19, 35] and after strabismus …