Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …

Central sensitization represents an enhancement in the function of neurons and circuits in
nociceptive pathways caused by increases in membrane excitability and synaptic efficacy as …

AMPA receptors (AMPARs) mediate the majority of fast excitatory synaptic transmission in
the brain. Dynamic changes in neuronal synaptic efficacy, termed synaptic plasticity, are …

S-Nitrosylation is a redox-mediated posttranslational modification that regulates protein
function via covalent reaction of nitric oxide (NO)-related species with a cysteine thiol group …

Nitric oxide (NO) is an important signaling molecule that is widely used in the nervous
system. With recognition of its roles in synaptic plasticity (long-term potentiation, LTP; long …

Oxidants are produced as a by-product of aerobic metabolism, and organisms ranging from
prokaryotes to mammals have evolved with an elaborate and redundant complement of …

Since the observation that nitric oxide (NO) can act as an intercellular messenger in the
brain, the past 25 years have witnessed the steady accumulation of evidence that it acts pre …

Nitric oxide is well established as a major signaling molecule. Evidence is accumulating that
carbon monoxide and hydrogen sulfide also are physiologic mediators in the …

AMPA-type glutamate receptors (AMPARs) mediate most fast excitatory synaptic
transmission in the brain. Diversity in excitatory signalling arises, in part, from functional …

Brain-derived neurotrophic factor (BDNF) and other neurotrophins have a vital role in the
development of the rat and mouse nervous system by influencing the expression of many …