Oral once-daily, fixed-dose, ledipasvir/sofosbuvir (Harvoni®)[±ribavirin] is approved in
several countries for the treatment of chronic hepatitis C (CHC) in adults and adolescents …

Hepatitis C infection is universal and the most common indication of liver transplantation in
the United States. The period of less effective interferon therapy with intolerable side effects …

Background This study aimed to evaluate the clinical effectiveness in terms of sustained
virological response and tolerability of available second generation direct-acting antivirals in …

Abstract Background and Objectives Hepatitis C treatment has changed considerably in
recent years, and many interferon (IFN)-free therapies are now available. Considering the …

Abstract Background and Objectives Second-generation direct-acting antivirals (DAAs) have
recently arisen as more effective and safer treatments for chronic hepatitis C. These drugs …

Aims To analyze the efficacy and safety of sofosbuvir (SOF)-based regimens in Thai patients
with chronic hepatitis C virus infection who had pre-existing significant liver fibrosis. Patients …

Abstract Background and Aim The efficacy of sofosbuvir (SOF)‐based regimens in the
treatment of chronic hepatitis C (HCV) patients with and without human immunodeficiency …

Hepatitis B is a DNA virus (HBV) that causes an acute and chronic infection. The HBV is
transmitted vertically from mother to child, from child to child, via sexual contacts, and …

Abstract What Is Known and Objective Sofosbuvir (SOF) is a new and highly effective
medication that dramatically improved hepatitis C virus (HCV) management. However …

Introdução: Recentemente, o manejo de pacientes infectados cronicamente pelo vírus da
Hepatite C tem progredido, incluindo os antivirais de ação direta (DAAs) de segunda …