[图书][B] Measurement of Kinetics of Sickle Hemoglobin Polymerization Using Absorbance: Implications for Therapy

EH Worth - 2023 - search.proquest.com
Therapeutic solutions to hinder the effects of sickle hemoglobin (HbS) polymerization are
highly sought after. Measuring the kinetics of polymerization of HbS using laser photolysis …

Voxelotor does not inhibit sickle hemoglobin fiber formation upon complete deoxygenation

EH Worth, MK Fugate, FA Ferrone - Biophysical Journal, 2023 - cell.com
The drug voxelotor (commercially known as Oxbryta) has been approved by the US Food
and Drug Administration for the treatment of sickle cell disease. It is known to reduce …