The landscape of the mesenchymal signature in brain tumours
The complexity of glioblastoma multiforme, the most common and lethal variant of gliomas,
is reflected by cellular and molecular heterogeneity at both the inter-and intra-tumoural …
is reflected by cellular and molecular heterogeneity at both the inter-and intra-tumoural …
[HTML][HTML] Studying human neurological disorders using induced pluripotent stem cells: from 2D monolayer to 3D organoid and blood brain barrier models
S Logan, T Arzua, SG Canfield… - Comprehensive …, 2019 - ncbi.nlm.nih.gov
Neurological disorders have emerged as a predominant healthcare concern in recent years
due to their severe consequences on quality of life and prevalence throughout the world …
due to their severe consequences on quality of life and prevalence throughout the world …
Blood–brain barrier disruption and its involvement in neurodevelopmental and neurodegenerative disorders
The blood–brain barrier (BBB) is a highly specialized and dynamic compartment which
regulates the uptake of molecules and solutes from the blood. The relevance of the …
regulates the uptake of molecules and solutes from the blood. The relevance of the …
Bilirubin-induced neurological damage: current and emerging iPSC-derived brain organoid models
AI Pranty, S Shumka, J Adjaye - Cells, 2022 - mdpi.com
Bilirubin-induced neurological damage (BIND) has been a subject of studies for decades,
yet the molecular mechanisms at the core of this damage remain largely unknown …
yet the molecular mechanisms at the core of this damage remain largely unknown …
Mesenchymal transformation: the rosetta stone of glioblastoma pathogenesis and therapy resistance
Z Azam, SST TO, BA Tannous - Advanced science, 2020 - Wiley Online Library
Despite decades of research, glioblastoma (GBM) remains invariably fatal among all forms
of cancers. The high level of inter‐and intratumoral heterogeneity along with its biological …
of cancers. The high level of inter‐and intratumoral heterogeneity along with its biological …
The great escape: the power of cancer stem cells to evade programmed cell death
Simple Summary Several current therapies fail to eradicate tumors due to the ability of
cancer stem cells (CSCs) to escape different programmed cell deaths. In fact, apoptosis …
cancer stem cells (CSCs) to escape different programmed cell deaths. In fact, apoptosis …
[HTML][HTML] Therapeutic effect of a hydrogel-based neural stem cell delivery sheet for mild traumatic brain injury
Objective: There are no effective clinically applicable treatments for neuronal dysfunction
after mild traumatic brain injury (TBI). Here, we evaluated the therapeutic effect of a new …
after mild traumatic brain injury (TBI). Here, we evaluated the therapeutic effect of a new …
Differentiation of human mesenchymal stem cells from Wharton's Jelly towards neural stem cells using a feasible and repeatable protocol
E Kruminis-Kaszkiel, A Osowski, E Bejer-Oleńska… - Cells, 2020 - mdpi.com
The transplantation of neural stem cells (NSCs) capable of regenerating to the cells of the
central nervous system (CNS) is a promising strategy in the treatment of CNS diseases and …
central nervous system (CNS) is a promising strategy in the treatment of CNS diseases and …
Human neural stem cells for cell-based medicinal products
B Fernandez-Muñoz, AB Garcia-Delgado… - Cells, 2021 - mdpi.com
Neural stem cells represent an attractive tool for the development of regenerative therapies
and are being tested in clinical trials for several neurological disorders. Human neural stem …
and are being tested in clinical trials for several neurological disorders. Human neural stem …
Modern advances in spinal cord regeneration: hydrogel combined with neural stem cells
O Rybachuk, Y Nesterenko, V Zhovannyk - Frontiers in Pharmacology, 2024 - frontiersin.org
Severe spinal cord injuries (SCI) lead to loss of functional activity of the body below the
injury site, affect a person's ability to self-care and have a direct impact on performance. Due …
injury site, affect a person's ability to self-care and have a direct impact on performance. Due …